MIER1 Antibody

ProSci
Product Code: PSI-28-101
Product Group: Primary Antibodies
Supplier: ProSci
CodeSizePrice
PSI-28-101-100ul100ul£609.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Rabbit
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
  • Canine (dog)
  • Fish
  • Human
  • Mouse
  • Rat
Applications:
  • Enzyme-Linked Immunosorbent Assay (ELISA)
  • Western Blot (WB)
Storage:
For short periods of storage (days) store at 4˚C. For longer periods of storage, store MIER1 antibody at -20˚C. As with any antibody avoid repeat freeze-thaw cycles.

Images

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Antibody used in WB on Human Jurkat 1.25 ug/ml.

Antibody used in WB on Human Jurkat 1.25 ug/ml.

Further Information

Additional Names:
MIER1, ER1, MI-ER1
Application Note:
MIER1 antibody can be used for detection of MIER1 by ELISA at 1:312500. MIER1 antibody can be used for detection of MIER1 by western blot at 1.25 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
Background:
The association of hMI-ER1 with Sp1 represents a novel mechanism for the negative regulation of Sp1 target promoters. Results demonstrate that alternate use of a facultative intron regulates the subcellular localization of hMI-ER1 proteins and this may have important implications for hMI-ER1 function in the regulation of transcription. Repressor activity is due to interaction and recruitment of a trichostatin A-sensitive histone deacetylase 1 (HDAC1).
Background References:
  • Paterno, G.D., et al., (1998) Gene 222 (1), 77-82.
Buffer:
Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Concentration:
batch dependent
Conjugate:
Unconjugated
Immunogen:
Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human MIER1.
NCBI Gene ID #:
57708
NCBI Official Name:
mesoderm induction early response 1, transcriptional regulator
NCBI Official Symbol:
MIER1
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
49 kDa
Protein Accession #:
NP_065999
Protein GI Number:
225735605
Purification:
Antibody is purified by protein A chromatography method.
Research Area:
Transcription ,Signal Transduction
Swissprot #:
Q8NES5
User NOte:
Optimal dilutions for each application to be determined by the researcher.