NR1D2 Antibody
| Code | Size | Price |
|---|
| PSI-28-893-100ul | 100ul | £609.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
- Canine (dog)
- Human
- Mouse
- Rat
Applications:
- Enzyme-Linked Immunosorbent Assay (ELISA)
- Western Blot (WB)
Storage:
For short periods of storage (days) store at 4˚C. For longer periods of storage, store NR1D2 antibody at -20˚C. As with any antibody avoid repeat freeze-thaw cycles.
Documents
Further Information
Additional Names:
NR1D2, RVR, BD73, EAR-1R
Application Note:
NR1D2 antibody can be used for detection of NR1D2 by ELISA at 1:62500. NR1D2 antibody can be used for detection of NR1D2 by western blot at 0.5 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
Background:
NR1D2 can interact with NCOA5 coactivator, leading to a strong increase of transcription of target genes. NR1D2 also binds to the sequences 5'-AATGTAGGTCA-3' and 5'-ATAACTAGGTCA-3' and acts as a potent competitive transcriptional silencer and negative regulator of RORalpha mediated trans-activation. NR1D2 may play different roles in metabolism, inflammation, and circadian cycling in the organ-specific manner in homeostasis.
Background References:
- Sauve, F., et al., (2001) Mol. Cell. Biol. 21 (1), 343-353.
Buffer:
Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Concentration:
batch dependent
Conjugate:
Unconjugated
Immunogen:
Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human NR1D2.
NCBI Gene ID #:
9975
NCBI Official Name:
nuclear receptor subfamily 1, group D, member 2
NCBI Official Symbol:
NR1D2
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
65 kDa
Protein Accession #:
NP_005117
Protein GI Number:
224177491
Purification:
Antibody is purified by protein A chromatography method.
Research Area:
Transcription ,Signal Transduction
Swissprot #:
Q14995
User NOte:
Optimal dilutions for each application to be determined by the researcher.