NR1I3 Antibody

ProSci
Product Code: PSI-27-919
Product Group: Primary Antibodies
Supplier: ProSci
CodeSizePrice
PSI-27-919-100ul100ul£609.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Rabbit
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Applications:
  • Enzyme-Linked Immunosorbent Assay (ELISA)
  • Western Blot (WB)
Storage:
For short periods of storage (days) store at 4˚C. For longer periods of storage, store NR1I3 antibody at -20˚C. As with any antibody avoid repeat freeze-thaw cycles.

Images

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Antibody used in WB on Human HepG2 at 1.25 ug/ml.

Antibody used in WB on Human HepG2 at 1.25 ug/ml.

Further Information

Additional Names:
NR1I3, CAR, CAR-BETA, CAR-SV1, CAR-SV10, CAR-SV11, CAR-SV12, CAR-SV13, CAR-SV14, CAR-SV15, CAR-SV17, CAR-SV18, CAR-SV19, CAR-SV20, CAR-SV21, CAR-SV4, CAR-SV6, CAR-SV7, CAR-SV8, CAR-SV9, CAR1, MB67, MGC97144
Application Note:
NR1I3 antibody can be used for detection of NR1I3 by ELISA at 1:62500. NR1I3 antibody can be used for detection of NR1I3 by western blot at 1.25 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
Background:
NR1I3 is a member of the nuclear receptor superfamily, and is a key regulator of xenobiotic and endobiotic metabolism. The protein binds to DNA as a monomer or a heterodimer with the retinoid X receptor and regulates the transcription of target genes involved in drug metabolism and bilirubin clearance, such as cytochrome P450 family members.
Background References:
  • Ferguson, S.S., (2005) Mol. Pharmacol. 68 (3), 747-757.
Buffer:
Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Concentration:
batch dependent
Conjugate:
Unconjugated
Immunogen:
Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human NR1I3.
NCBI Gene ID #:
9970
NCBI Official Name:
nuclear receptor subfamily 1, group I, member 3
NCBI Official Symbol:
NR1I3
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
40 kDa, 38 kDa, 32 kDa, 35 kDa, 37 kDa, 36 kDa, 33 kDa, 30 kDa, 35 kDa, 35 kDa, 38 kDa, 36 kDa, 40 kDa, 36 kDa, 40 kDa
Protein Accession #:
NP_005113
Protein GI Number:
4826661
Purification:
Antibody is purified by protein A chromatography method.
Research Area:
Transcription ,Signal Transduction
Swissprot #:
Q5VTW5
User NOte:
Optimal dilutions for each application to be determined by the researcher.