NR2C2 Antibody
| Code | Size | Price |
|---|
| PSI-25-422-100ul | 100ul | £662.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Applications:
- Enzyme-Linked Immunosorbent Assay (ELISA)
- Western Blot (WB)
Storage:
For short periods of storage (days) store at 4˚C. For longer periods of storage, store NR2C2 antibody at -20˚C. As with any antibody avoid repeat freeze-thaw cycles.
Documents
Further Information
Additional Names:
NR2C2, TAK1, TR2R1, TR4, hTAK1
Application Note:
NR2C2 antibody can be used for detection of NR2C2 by ELISA at 1:312500. NR2C2 antibody can be used for detection of NR2C2 by western blot at 1 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
Background:
Members of the nuclear hormone receptor family, such as NR2C2, act as ligand-activated transcription factors. The proteins have an N-terminal transactivation domain, a central DNA-binding domain with 2 zinc fingers, and a ligand-binding domain at the C terminus. The activated receptor/ligand complex is translocated to the nucleus where it binds to hormone response elements of target genes. Members of the nuclear hormone receptor family, such as NR2C2, act as ligand-activated transcription factors. The proteins have an N-terminal transactivation domain, a central DNA-binding domain with 2 zinc fingers, and a ligand-binding domain at the C terminus. The activated receptor/ligand complex is translocated to the nucleus where it binds to hormone response elements of target genes (Yoshikawa et al., 1996 [PubMed 8661150]).
Background References:
- Bouwmeester, T., (2004) Nat. Cell Biol. 6 (2), 97-105.
Buffer:
Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Concentration:
batch dependent
Conjugate:
Unconjugated
Immunogen:
Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human NR2C2.
NCBI Gene ID #:
7182
NCBI Official Name:
nuclear receptor subfamily 2, group C, member 2
NCBI Official Symbol:
NR2C2
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
67 kDa
Protein Accession #:
NP_003289
Protein GI Number:
36950991
Purification:
Antibody is purified by peptide affinity chromatography method.
Research Area:
Transcription ,Signal Transduction ,Neuroscience
Swissprot #:
P49116
User NOte:
Optimal dilutions for each application to be determined by the researcher.