CDK2 Antibody
| Code | Size | Price |
|---|
| PSI-79-165-0.1mg | 0.1mg | £488.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
- Human
- Mouse
- Rat
Applications:
- Immunohistochemistry (IHC)
- Western Blot (WB)
Storage:
Store antibody at -20˚C for up to one year.
Documents
Further Information
Additional Names:
CDKN2, p33(CDK2), JNKK1, MEK4, MKK4, PRKMK4, SEK1, SERK1, SKK1, kinase Cdk2, p33 protein kinase
Application Note:
Western Blot: 1:500~1:1000, Immunohistochemistry: 1:50~1:100
Background:
Involved in the control of the cell cycle. Interacts with cyclins A, B1, B3, D, or E. Activity of CDK2 is maximal during S phase and G2.
Background References:
- Ukomadu C, et al. (2003) J Biol Chem; 278 (7): 4840-6. Morris MC, et al. (2002) J Biol Chem; 277 (26): 23847-53. Brown NR, et al. (1999) J Biol Chem; 274 (13): 8746-56. Liu Y, et al. (2004) J Biol Chem; 279 (6): 4507-14.
Buffer:
Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Concentration:
1 mg/mL
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
CDK2 (Phospho-Thr160) antibody was raised against a peptide sequence around phosphorylation site of threonine 160 (T-Y-T (p) -H-E) derived from Human CDK2.
Modifications:
Phospho-Specific
NCBI Gene ID #:
1017
NCBI Official Name:
cyclin-dependent kinase 2
NCBI Official Symbol:
CDK2
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
34 kDa
Protein Accession #:
NP_001789.2
Protein GI Number:
16936528
Purification:
Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy using non-phosphopeptide.
Research Area:
Phospho-Specific,Apoptosis,Cancer,Cell Cycle
SPECIFICITY:
This antibody detects endogenous level of CDK2 only when phosphorylated at threonine 160.
Swissprot #:
P24941