Elk-1 Antibody
| Code | Size | Price |
|---|
| PSI-79-255-0.1mg | 0.1mg | £481.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
- Human
- Mouse
- Rat
Application: Immunohistochemistry (IHC)
Storage:
Store antibody at -20˚C for up to one year.
Documents
Further Information
Additional Names:
Mek5, Mkk5, Prkmk5, ELK1, ETS-domain protein Elk-1
Application Note:
Immunohistochemistry: 1:50~1:100
Background:
Elk-1 is a member of the Ets family of transcription factors and of the ternary complex factor (TCF) subfamily. Proteins of the TCF subfamily form a ternary complex by binding to the the serum response factor and the serum reponse element in the promoter of the c-fos proto-oncogene. The protein encoded by this gene is a nuclear target for the ras-raf-MAPK signaling cascade. Alternatively spliced transcript variants encoding the same protein have been found for this gene
Background References:
- Xing J, et al. (1996) Science. 273 (5277): 959-963. Janknecht R, et al. (1993) EMBO J. 12 (13): 5097-5104. Marais R, et al. (1993) Cell 73: 381-393. Kortenjann M, et al. (1994) Mol Cell Biol. 14: 4815-4824. Cavigelli M, et al. (1995) EMBO J. 14: 5957-5964. Whitmarsh A J, et al. (1995) Science. 269:403-407.
Buffer:
Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Concentration:
1 mg/mL
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
Elk-1 (Ab-383) antibody was raised against a peptide sequence around aa.381~385 (T-L-S-P-I) derived from Human Elk1.
NCBI Gene ID #:
2002
NCBI Official Name:
ELK1, member of ETS oncogene family
NCBI Official Symbol:
ELK1
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
47 kDa
Protein Accession #:
NP_001107595.1
Protein GI Number:
166362732
Purification:
Antibodies were purified by affinity-chromatography using epitope-specific peptide.
Research Area:
Other
SPECIFICITY:
This antibody detects endogenous level of total Elk-1 protein.
Swissprot #:
P19419