Neurobeachin Antibody
| Code | Size | Price |
|---|
| PSI-45-951-0.1mg | 0.1mg | £626.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Caprine (Goat)
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
- Human
- Mouse
Applications:
- Enzyme-Linked Immunosorbent Assay (ELISA)
- Western Blot (WB)
Storage:
Aliquot and store at -20˚C. Minimize freezing and thawing.
Documents
Further Information
Additional Names:
NBEA, neurobeachin, RP11-270C18.1, BCL8B, FLJ10197, KIAA1544, LYST2, lysosomal trafficking regulator, lysosomal trafficking regulator 2
Application Note:
Peptide ELISA: antibody detection limit dilution 1:4000.Western Blot:Approx 300kDa band observed in lysates of transfected HEK293 and endogenously in lysates of insulinoma cell line B-TC3 (calculated MW of 327kDa according to NP_056493.3). Data from a previous goat. Data kindly provided by Professor John Creemers, K.U. Leuven, Belgium. Recommended concentration: 1-3ug/ml.Immunohistochemistry:In paraffin embedded Human Cerebral Cortex shows textured cytoplasm staining in the neuronal cell bodies. Recommended concentration: 5-10ug/ml.
Background References:
- Wang X, Herberg FW, Laue MM, Wullner C, Hu B, Petrasch-Parwez E, Kilimann MW. Neurobeachin: A protein kinase A-anchoring, beige/Chediak-higashi protein homolog implicated in neuronal membrane traffic. J Neurosci 2000 Dec 1;20(23):8551-65
Buffer:
Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin.
Aliquot and store at -20?C. Minimize freezing and thawing.
Concentration:
500 ug/mL
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Homology:
Expected Species Reactivity based on sequence homology: Mouse, Dog, Cow
Immunogen:
The immunogen for this antibody is: C-DFNRWHYEHQNRY
NCBI Gene ID #:
26960
NCBI Official Name:
neurobeachin
NCBI Official Symbol:
NBEA
NCBI Organism:
Homo sapiens
Physical State:
Liquid
Protein Accession #:
NP_056493.3, NP_001191126.1
Protein GI Number:
62422577
Purification:
Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Research Area:
Cancer
SPECIFICITY:
This antibody is expected to recognise isoform 1 (NP_056493.3) and isoform 2 (NP_001191126.1).
Swissprot #:
Q8NFP9