Neuroserpin Antibody

ProSci
Product Code: PSI-45-961
Product Group: Primary Antibodies
Supplier: ProSci
CodeSizePrice
PSI-45-961-0.1mg0.1mg£626.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Caprine (Goat)
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Applications:
  • Enzyme-Linked Immunosorbent Assay (ELISA)
  • Western Blot (WB)
Storage:
Aliquot and store at -20˚C. Minimize freezing and thawing.

Images

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45-961 (1ug/ml) staining of Human Brain lysate (35ug protein in RIPA buffer). Detected by chemiluminescence.
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45-961 (1ug/ml) staining of Human Brain lysate (35ug protein in RIPA buffer). Detected by chemiluminescence.

Further Information

Additional Names:
SERPINI1, neuroserpin, PI12, serine (or cysteine) proteinase inhibitor, clade I (neuroserpin), member 1, protease inhibitor 12 (neuroserpin), serpin peptidase inhibitor, clade I (neuroserpin), member 1, DKFZp781N13156
Application Note:
Peptide ELISA: antibody detection limit dilution 1:32000.Western Blot:Approx 48kDa band observed in Human Brain lysate (calculated MW of 46.4kDa according to NP_005016.1). Recommended concentration: 1-3ug/ml. Primary incubation was 1 hour.Immunohistochemistry:Paraffin embedded Human Brain (Cortex). Recommended concentration: 5ug/ml.
Background References:
  • Onda M, Belorgey D, Sharp LK, Lomas DA. Latent Ser49Pro neuroserpin forms polymers in the dementia familial encephalopathy with neuroserpin inclusion bodies. J Biol Chem. 2005 Jan 21;
Buffer:
Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. Aliquot and store at -20?C. Minimize freezing and thawing.
Concentration:
500 ug/mL
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Homology:
Expected Species Reactivity based on sequence homology: Mouse, Rat, Pig, Cow
Immunogen:
The immunogen for this antibody is: C-TMNTSGHDFEEL
NCBI Gene ID #:
5274
NCBI Official Name:
serpin peptidase inhibitor, clade I (neuroserpin), member 1
NCBI Official Symbol:
SERPINI1
NCBI Organism:
Homo sapiens
Physical State:
Liquid
Protein Accession #:
NP_005016.1
Protein GI Number:
4826904
Purification:
Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Research Area:
Cancer
SPECIFICITY:
Reported variants represent identical protein (NP_005016.1; NP_001116224.1).
Swissprot #:
Q99574