ACO2 Antibody

ProSci
Product Code: PSI-27-083
Product Group: Primary Antibodies
Supplier: ProSci
CodeSizePrice
PSI-27-083-100ul100ul£662.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Rabbit
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
  • C. Elegans
  • Human
  • Mouse
  • Rat
Applications:
  • Enzyme-Linked Immunosorbent Assay (ELISA)
  • Western Blot (WB)
Storage:
For short periods of storage (days) store at 4˚C. For longer periods of storage, store ACO2 antibody at -20˚C. As with any antibody avoid repeat freeze-thaw cycles.

Images

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Antibody used in WB on Human Heart at 0.2-1 ug/ml.
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Antibody used in WB on Human 721_B cells at 1 ug/ml.

Antibody used in WB on Human Heart at 0.2-1 ug/ml.
Antibody used in WB on Human 721_B cells at 1 ug/ml.

Further Information

Additional Names:
ACO2, ACONM, MGC20605, MGC33908, ICRD
Application Note:
ACO2 antibody can be used for detection of ACO2 by ELISA at 1:312500. ACO2 antibody can be used for detection of ACO2 by western blot at 1 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
Background:
ACO2 belongs to the aconitase/IPM isomerase family. It is an enzyme that catalyzes the interconversion of citrate to isocitrate via cis-aconitate in the second step of the TCA cycle. This protein is encoded in the nucleus and functions in the mitochondrion. It was found to be one of the mitochondrial matrix proteins that are preferentially degraded by the serine protease 15 (PRSS15), also known as Lon protease, after oxidative modification.The protein encoded by this gene belongs to the aconitase/IPM isomerase family. It is an enzyme that catalyzes the interconversion of citrate to isocitrate via cis-aconitate in the second step of the TCA cycle. This protein is encoded in the nucleus and functions in the mitochondrion. It was found to be one of the mitochondrial matrix proteins that are preferentially degraded by the serine protease 15 (PRSS15), also known as Lon protease, after oxidative modification. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Background References:
  • Yu, Z., (2006) Prostate 66 (10), 1061-1069.
Buffer:
Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Concentration:
batch dependent
Conjugate:
Unconjugated
Immunogen:
Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human ACO2.
NCBI Gene ID #:
50
NCBI Official Name:
aconitase 2, mitochondrial
NCBI Official Symbol:
ACO2
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
82 kDa
Protein Accession #:
NP_001089
Protein GI Number:
4501867
Purification:
Antibody is purified by peptide affinity chromatography method.
Research Area:
Cancer
Swissprot #:
Q99798
User NOte:
Optimal dilutions for each application to be determined by the researcher.