MRP5 Antibody

ProSci
Product Code: PSI-45-903
Product Group: Primary Antibodies
Supplier: ProSci
CodeSizePrice
PSI-45-903-0.1mg0.1mg£626.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Caprine (Goat)
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Applications:
  • Enzyme-Linked Immunosorbent Assay (ELISA)
  • Western Blot (WB)
Storage:
Aliquot and store at -20˚C. Minimize freezing and thawing.

Images

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45-903 (0.5ug/ml) staining of Human Frontal Cortex lysate (35ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.
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45-903 (0.5ug/ml) staining of Human Frontal Cortex lysate (35ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.

Further Information

Additional Names:
MRP5, DKFZp686C1782, ABCC5, ATP-binding cassette, sub-family C (CFTR/MRP), member 5, ABC33, EST277145, MOAT-C, MOATC, SMRP, pABC11, ATP-binding cassette, sub-family C, member 5, canalicular multispecific organic anion transporter C
Application Note:
Peptide ELISA: antibody detection limit dilution 1:32000.Western Blot:Approx. 150kDa band observed in Human Brain (Frontal Cortex) lysates (calculated MW of 161kDa according to NP_005679.2). Recommended concentration: 0.5-1.5ug/ml.Immunohistochemistry:In paraffin embedded Human Kidney shows membranous staining in DCT. Paraffin embedded Human Liver. Recommended concentration: 4-6ug/ml.
Background References:
  • Meyer Zu Schwabedissen HE, Grube M, Heydrich B, Linnemann K, Fusch C, Kroemer HK, Jedlitschky G. Expression, localization, and function of MRP5 (ABCC5), a transporter for cyclic nucleotides, in human placenta and cultured human trophoblasts: effects of gestational age and cellular differentiation Am J Pathol. 2005 Jan;166(1):39-48.
Buffer:
Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. Aliquot and store at -20?C. Minimize freezing and thawing.
Concentration:
500 ug/mL
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Homology:
Expected Species Reactivity based on sequence homology: Mouse, Rat, Dog, Pig, Cow
Immunogen:
The immunogen for this antibody is: KDIDIGKEYIIP-C
NCBI Gene ID #:
10057
NCBI Official Name:
ATP-binding cassette, sub-family C (CFTR/MRP), member 5
NCBI Official Symbol:
ABCC5
NCBI Organism:
Homo sapiens
Physical State:
Liquid
Protein Accession #:
NP_005679.2, NP_001018881.1
Protein GI Number:
66529005
Purification:
Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Research Area:
Cancer
SPECIFICITY:
This antibody is expected to recognize both reported isoforms (NP_005679.2; NP_001018881.1).
Swissprot #:
O15440