ProSci

GPX3 Antibody

Product Code:
 
PSI-29-588
Product Group:
 
Primary Antibodies
Supplier:
 
ProSci
Host Type:
 
Rabbit
Antibody Clonality:
 
Polyclonal
Regulatory Status:
 
RUO
Target Species:
  • Human
  • Mouse
  • Rat
Applications:
  • Enzyme-Linked Immunosorbent Assay (ELISA)
  • Western Blot (WB)
Storage:
 
For short periods of storage (days) store at 4˚C. For longer periods of storage, store GPX3 antibody at -20˚C. As with any antibody avoid repeat freeze-thaw cycles.
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Antibody used in WB on Human HepG2 cells at 0.2-1 ug/ml.
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Antibody used in WB on Human HepG2 cells at 0.2-1 ug/ml.

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PSI-29-588-100ul100ul£662.00
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Further Information

Additional Names:
GPX3, GPx-P, GSHPx-3, GSHPx-P
Application Note:
GPX3 antibody can be used for detection of GPX3 by ELISA at 1:312500. GPX3 antibody can be used for detection of GPX3 by western blot at 1.0 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
Background:
GPX3 belongs to the glutathione peroxidase family, which functions in the detoxification of hydrogen peroxide. It contains a selenocysteine (Sec) residue at its active site. The selenocysteine is encoded by the UGA codon, which normally signals translation termination.Glutathione peroxidase catalyzes the reduction of hydrogen peroxide, organic hydroperoxide, and lipid peroxides by reduced glutathione and functions in the protection of cells against oxidative damage. Human plasma glutathione peroxidase has been shown to be a selenium-containing enzyme. GPX3 expression appears to be tissue-specific.
Background References:
  • Lee, O.J., (2005) Neoplasia 7 (9), 854-861.
Buffer:
Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Concentration:
batch dependent
Conjugate:
Unconjugated
Immunogen:
Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human GPX3.
NCBI Gene ID #:
2878
NCBI Official Name:
glutathione peroxidase 3 (plasma)
NCBI Official Symbol:
GPX3
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
25 kDa
Protein Accession #:
NP_002075
Protein GI Number:
6006001
Purification:
Antibody is purified by peptide affinity chromatography method.
Research Area:
Cancer ,Signal Transduction
Swissprot #:
P22352
User NOte:
Optimal dilutions for each application to be determined by the researcher.