ProSci

MMP19 Antibody

Product Code:
 
PSI-27-549
Product Group:
 
Primary Antibodies
Supplier:
 
ProSci
Host Type:
 
Rabbit
Antibody Clonality:
 
Polyclonal
Regulatory Status:
 
RUO
Target Species:
 
Human
Applications:
  • Enzyme-Linked Immunosorbent Assay (ELISA)
  • Immunohistochemistry (IHC)
  • Western Blot (WB)
Storage:
 
For short periods of storage (days) store at 4˚C. For longer periods of storage, store MMP19 antibody at -20˚C. As with any antibody avoid repeat freeze-thaw cycles.
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Antibody used in IHC on Human urinary bladder.
2 / 4
3 / 4
Antibody used in WB on Human HepG2 at 5.0-10.0 ug/ml.
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Antibody used in IHC on Human at: 1:100.
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Antibody used in IHC on Human urinary bladder.
Antibody used in WB on Human HepG2 at 5.0-10.0 ug/ml.
Antibody used in IHC on Human at: 1:100.

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PSI-27-549-100ul100ul£609.00
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Typical lead time: 14-21 working days.
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Further Information

Additional Names:
MMP19, MMP18, RASI-1
Application Note:
MMP19 antibody can be used for detection of MMP19 by ELISA at 1:1562500. MMP19 antibody can be used for detection of MMP19 by western blot at 5.0-10.0 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
Background:
Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling. They are also involved in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. The function of the protein encoded by this gene has not been determined. This gene was previously referred to as MMP18 but has been renamed matrix metalloproteinase 19 (MMP19). Multiple transcript variants encoding distict isoforms have been identified for this gene.
Background References:
  • Sadowski, T., et al., (2003) Mol. Biol. Cell 14 (11), 4569-4580.
Buffer:
Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Concentration:
batch dependent
Conjugate:
Unconjugated
Immunogen:
Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human MMP19.
NCBI Gene ID #:
4327
NCBI Official Name:
matrix metallopeptidase 19
NCBI Official Symbol:
MMP19
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
56 kDa
Protein Accession #:
NP_002420
Protein GI Number:
4505213
Purification:
Antibody is purified by protein A chromatography method.
Research Area:
Cancer ,Signal Transduction
Swissprot #:
Q99542
User NOte:
Optimal dilutions for each application to be determined by the researcher.