ProSci

MMP9 Antibody

Product Code:
 
PSI-27-785
Product Group:
 
Primary Antibodies
Supplier:
 
ProSci
Host Type:
 
Rabbit
Antibody Clonality:
 
Polyclonal
Regulatory Status:
 
RUO
Target Species:
  • Canine (dog)
  • Fish
  • Human
  • Mouse
  • Rat
Applications:
  • Enzyme-Linked Immunosorbent Assay (ELISA)
  • Western Blot (WB)
Storage:
 
For short periods of storage (days) store at 4˚C. For longer periods of storage, store MMP9 antibody at -20˚C. As with any antibody avoid repeat freeze-thaw cycles.
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Antibody used in IHC on Mouse prostate cancer at 2-15 ug/ml.
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Antibody used in IHC on Mouse prostate cancer at 2-15 ug/ml.

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PSI-27-785-100ul100ul£609.00
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Further Information

Additional Names:
MMP9, GELB, CLG4B, MMP-9, MANDP2
Application Note:
MMP9 antibody can be used for detection of MMP9 by ELISA at 1:62500. MMP9 antibody can be used for detection of MMP9 by western blot at 1.25 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
Background:
Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. The enzyme encoded by MMP9 degrades type IV and V collagens. Studies in rhesus monkeys suggest that the enzyme is involved in IL-8-induced mobilization of hematopoietic progenitor cells from bone marrow, and murine studies suggest a role in tumor-associated tissue remodeling.
Background References:
  • Nozell, S., et al., (2004) J. Biol. Chem. 279 (37), 38577-38589.
Buffer:
Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Concentration:
batch dependent
Conjugate:
Unconjugated
Immunogen:
Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human MMP9.
NCBI Gene ID #:
4318
NCBI Official Name:
matrix metallopeptidase 9 (gelatinase B, 92kDa gelatinase, 92kDa type IV collagenase)
NCBI Official Symbol:
MMP9
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
78 kDa
Protein Accession #:
NP_004985
Protein GI Number:
74272287
Purification:
Antibody is purified by protein A chromatography method.
Research Area:
Cancer ,Signal Transduction
Swissprot #:
P14780
User NOte:
Optimal dilutions for each application to be determined by the researcher.