MAP3K7IP2 Antibody
| Code | Size | Price |
|---|
| PSI-27-585-100ul | 100ul | £662.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
- Canine (dog)
- Human
- Mouse
- Rat
Applications:
- Enzyme-Linked Immunosorbent Assay (ELISA)
- Immunohistochemistry (IHC)
- Western Blot (WB)
Storage:
For short periods of storage (days) store at 4˚C. For longer periods of storage, store MAP3K7IP2 antibody at -20˚C. As with any antibody avoid repeat freeze-thaw cycles.
Documents
Further Information
Additional Names:
MAP3K7IP2, CHTD2, MAP3K7IP2
Application Note:
MAP3K7IP2 antibody can be used for detection of MAP3K7IP2 by ELISA at 1:312500. MAP3K7IP2 antibody can be used for detection of MAP3K7IP2 by western blot at 2.0/mL.
Background:
MAP3K7IP2 is an activator of MAP3K7/TAK1, which is required for for the IL-1 induced activation of NF.:B and MAPK8/JNK. This protein forms a kinase complex with TRAF6, MAP3K7 and TAB1, thus serving as an adaptor linking MAP3K7 and TRAF6. This protein, TAB1, and MAP3K7 also participate in the signal transduction induced by TNFSF11/RANKl through the activation of the receptor activator of NF.:B (TNFRSF11A/RANK), which may regulate the development and function of osteoclasts.
Background References:
- Kanayama, A., et al., , (2004) Mol. Cell 15 (4), 535-548.
Buffer:
Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Concentration:
batch dependent
Conjugate:
Unconjugated
Immunogen:
Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human MAP3K7IP2.
NCBI Gene ID #:
23118
NCBI Official Name:
TGF-beta activated kinase 1/MAP3K7 binding protein 2
NCBI Official Symbol:
TAB2
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
76 kDa
Protein Accession #:
NP_055908
Protein GI Number:
14149669
Purification:
Antibody is purified by peptide affinity chromatography method.
Research Area:
Cancer ,Signal Transduction ,Immunology
Swissprot #:
Q9NYJ8
User NOte:
Optimal dilutions for each application to be determined by the researcher.