CACNA1C Antibody

ProSci
Product Code: PSI-46-820
Product Group: Primary Antibodies
Supplier: ProSci
CodeSizePrice
PSI-46-820-0.1mg0.1mg£626.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Caprine (Goat)
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Applications:
  • Enzyme-Linked Immunosorbent Assay (ELISA)
  • Western Blot (WB)
Storage:
Aliquot and store at -20˚C. Minimize freezing and thawing.

Images

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46-820 (1ug/ml) staining of Human Heart lysate (35ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.

46-820 (1ug/ml) staining of Human Heart lysate (35ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.

Further Information

Additional Names:
CACNA1C, calcium channel, voltage-dependent, L type, alpha 1C subunit, CACH2, CACN2, CACNL1A1, CCHL1A1, CaV1.2, MGC120730, TS, DHPR, alpha-1 subunit, calcium channel, L type, alpha 1 polypeptide, isoform 1, cardic muscle, calcium channel, cardic dihydropyridine-sensitive, alpha-1 subunit, voltage-dependent L-type calcium channel alpha 1C subunit, voltage-gated L-type calcium channel Cav1.2 alpha 1 subunit, splice variant 10*, voltage-gated calcium channel alpha subunit Cav1.2
Application Note:
Peptide ELISA: antibody detection limit dilution 1:64000.Western Blot:Approx. 200kDa band observed in Human Heart lysate (calculated MW of 240kDa according to NP_000710.5). Recommended concentration: 1.0-3.0ug/ml.
Background References:
  • Saud ZA, Minobe E, Wang WY, Han DY, Horiuchi M, Hao LY, Kameyama M. Calpastatin binds to a calmodulin-binding site of cardiac Cav1.2 Ca2+ channels. Biochem Biophys Res Commun. 2007 Dec 14;364(2):372-7. Epub 2007 Oct 15.
Buffer:
Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. Aliquot and store at -20?C. Minimize freezing and thawing.
Concentration:
500 ug/mL
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
The immunogen for this antibody is: C-RARGRPSEEELQD
NCBI Gene ID #:
775
NCBI Official Name:
calcium channel, voltage-dependent, L type, alpha 1C subunit
NCBI Official Symbol:
CACNA1C
NCBI Organism:
Homo sapiens
Physical State:
Liquid
Protein Accession #:
NP_000710.5, NP_955630.2, NP_001161097.1, NP_001123299.1, NP_001123301.1, NP_001161096.1, NP_001123302.1, NP_001123303.1 and more
Protein GI Number:
120433602
Purification:
Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Research Area:
Signal Transduction ,Neuroscience
SPECIFICITY:
This antibody is expected to recognise all reported human isoforms.
Swissprot #:
Q13936