TERF2 Antibody

ProSci
Product Code: PSI-27-304
Product Group: Primary Antibodies
Supplier: ProSci
CodeSizePrice
PSI-27-304-100ul100ul£609.00
Quantity:
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Overview

Host Type: Rabbit
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Applications:
  • Enzyme-Linked Immunosorbent Assay (ELISA)
  • Western Blot (WB)
Storage:
For short periods of storage (days) store at 4˚C. For longer periods of storage, store TERF2 antibody at -20˚C. As with any antibody avoid repeat freeze-thaw cycles.

Images

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Antibody used in WB on Transfected 293T at 5.0 ug/ml.

Antibody used in WB on Transfected 293T at 5.0 ug/ml.

Further Information

Additional Names:
TERF2, TRBF2, TRF2
Application Note:
TERF2 antibody can be used for detection of TERF2 by ELISA at 1:62500. TERF2 antibody can be used for detection of TERF2 by western blot at 5.0 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
Background:
TERF2 is a telomere specific protein, TERF2, which is a component of the telomere nucleoprotein complex. This protein is present at telomeres in metaphase of the cell cycle, is a second negative regulator of telomere length and plays a key role in the protective activity of telomeres. While having similar telomere binding activity and domain organization, TERF2 differs from TERF1 in that its N terminus is basic rather than acidic.This gene encodes a telomere specific protein, TERF2, which is a component of the telomere nucleoprotein complex. This protein is present at telomeres in metaphase of the cell cycle, is a second negative regulator of telomere length and plays a key role in the protective activity of telomeres. While having similar telomere binding activity and domain organization, TERF2 differs from TERF1 in that its N terminus is basic rather than acidic. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Background References:
  • Etheridge, K.T., (2008) J. Biol. Chem. 283 (11), 6935-6941.
Buffer:
Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Concentration:
batch dependent
Conjugate:
Unconjugated
Immunogen:
Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human TERF2.
NCBI Gene ID #:
7014
NCBI Official Name:
telomeric repeat binding factor 2
NCBI Official Symbol:
TERF2
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
55 kDa
Protein Accession #:
NP_005643
Protein GI Number:
429535832
Purification:
Antibody is purified by protein A chromatography method.
Research Area:
Cell Cycle
Swissprot #:
Q15554
User NOte:
Optimal dilutions for each application to be determined by the researcher.