MCM5 Antibody

ProSci
Product Code: PSI-28-541
Product Group: Primary Antibodies
Supplier: ProSci
CodeSizePrice
PSI-28-541-100ul100ul£609.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Rabbit
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Applications:
  • Enzyme-Linked Immunosorbent Assay (ELISA)
  • Western Blot (WB)
Storage:
For short periods of storage (days) store at 4˚C. For longer periods of storage, store MCM5 antibody at -20˚C. As with any antibody avoid repeat freeze-thaw cycles.

Images

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Antibody used in WB on Human HepG2 at 2.5 ug/ml.

Antibody used in WB on Human HepG2 at 2.5 ug/ml.

Further Information

Additional Names:
MCM5, CDC46, P1-CDC46
Application Note:
MCM5 antibody can be used for detection of MCM5 by ELISA at 1:62500. MCM5 antibody can be used for detection of MCM5 by western blot at 2.5 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
Background:
The protein encoded by MCM5 is structurally very similar to the CDC46 protein from S. cerevisiae, a protein involved in the initiation of DNA replication. The encoded protein is a member of the MCM family of chromatin-binding proteins and can interact with at least two other members of this family. The encoded protein is upregulated in the transition from the G0 to G1/S phase of the cell cycle and may actively participate in cell cycle regulation.
Background References:
  • Ohtani, K., et al., (1999) Oncogene 18 (14), 2299-2309.
Buffer:
Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Concentration:
batch dependent
Conjugate:
Unconjugated
Immunogen:
Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human MCM5.
NCBI Gene ID #:
4174
NCBI Official Name:
minichromosome maintenance complex component 5
NCBI Official Symbol:
MCM5
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
82 kDa
Protein Accession #:
NP_006730
Protein GI Number:
23510448
Purification:
Antibody is purified by protein A chromatography method.
Research Area:
Cell Cycle ,Cancer
Swissprot #:
P33992
User NOte:
Optimal dilutions for each application to be determined by the researcher.