MCM7 Antibody
| Code | Size | Price |
|---|
| PSI-28-540-100ul | 100ul | £609.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Applications:
- Enzyme-Linked Immunosorbent Assay (ELISA)
- Western Blot (WB)
Storage:
For short periods of storage (days) store at 4˚C. For longer periods of storage, store MCM7 antibody at -20˚C. As with any antibody avoid repeat freeze-thaw cycles.
Documents
Further Information
Additional Names:
MCM7, MCM2, CDC47, P85MCM, P1CDC47, PNAS146, P1.1-MCM3
Application Note:
MCM7 antibody can be used for detection of MCM7 by ELISA at 1:62500. MCM7 antibody can be used for detection of MCM7 by western blot at 2.5 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
Background:
MCM7 encodes a protein that is one of the highly conserved mini-chromosome maintenance proteins (MCM) that are essential for the initiation of eukaryotic genome replication. The hexameric protein complex formed by the MCM proteins is a key component of the pre-replication complex (pre_RC) and may be involved in the formation of replication forks and in the recruitment of other DNA replication related proteins. The MCM complex consisting of this protein and MCM2, 4 and 6 proteins possesses DNA helicase activity, and may act as a DNA unwinding enzyme. Cyclin D1-dependent kinase, CDK4, is found to associate with this protein, and may regulate the binding of this protein with the tumorsuppressor protein RB1/RB.
Background References:
- Suzuki, S., et al., (1998) Gene. 216(1), 85-91.
Buffer:
Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Concentration:
batch dependent
Conjugate:
Unconjugated
Immunogen:
Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human MCM7.
NCBI Gene ID #:
4176
NCBI Official Name:
minichromosome maintenance complex component 7
NCBI Official Symbol:
MCM7
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
42 kDa, 81 kDa
Protein Accession #:
AAH09398
Protein GI Number:
14424779
Purification:
Antibody is purified by protein A chromatography method.
Research Area:
Cell Cycle ,Cancer
Swissprot #:
P33993-2
User NOte:
Optimal dilutions for each application to be determined by the researcher.