RRM2 Antibody
| Code | Size | Price |
|---|
| PSI-26-094-100ul | 100ul | £662.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Applications:
- Enzyme-Linked Immunosorbent Assay (ELISA)
- Western Blot (WB)
Storage:
For short periods of storage (days) store at 4˚C. For longer periods of storage, store RRM2 antibody at -20˚C. As with any antibody avoid repeat freeze-thaw cycles.
Documents
Further Information
Additional Names:
RRM2, R2, RR2M, RR2
Application Note:
RRM2 antibody can be used for detection of RRM2 by ELISA at 1:1562500. RRM2 antibody can be used for detection of RRM2 by western blot at 1 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
Background:
RRM2 provides the precursors necessary for DNA synthesis. RRM2 catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. RRM2 inhibits Wnt signaling.Ribonucleotide reductase catalyzes the formation of deoxyribonucleotides from ribonucleotides. It is composed of 2 non-identical subunits, proteins M1 and M2. Synthesis of M2 is regulated in a cell-cycle dependent fashion. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Background References:
- Souglakos, J., (2008) Br. J. Cancer 98 (10), 1710-1715.
Buffer:
Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Concentration:
batch dependent
Conjugate:
Unconjugated
Immunogen:
Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human RRM2.
NCBI Gene ID #:
6241
NCBI Official Name:
ribonucleotide reductase M2
NCBI Official Symbol:
RRM2
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
45 kDa
Protein Accession #:
NP_001025
Protein GI Number:
4557845
Purification:
Antibody is purified by peptide affinity chromatography method.
Research Area:
Cell Cycle ,Cancer
Swissprot #:
P31350
User NOte:
Optimal dilutions for each application to be determined by the researcher.