PBK Antibody

ProSci
Product Code: PSI-26-354
Product Group: Primary Antibodies
Supplier: ProSci
CodeSizePrice
PSI-26-354-100ul100ul£662.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Rabbit
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
  • Human
  • Mouse
  • Rat
Applications:
  • Enzyme-Linked Immunosorbent Assay (ELISA)
  • Western Blot (WB)
Storage:
For short periods of storage (days) store at 4˚C. For longer periods of storage, store PBK antibody at -20˚C. As with any antibody avoid repeat freeze-thaw cycles.

Images

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Antibody used in WB on Human 721_B at 0.2-1 ug/ml.

Antibody used in WB on Human 721_B at 0.2-1 ug/ml.

Further Information

Additional Names:
PBK, FLJ14385, Nori-3, SPK, TOPK, CT84, HEL164
Application Note:
PBK antibody can be used for detection of PBK by ELISA at 1:62500. PBK antibody can be used for detection of PBK by western blot at 1 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
Background:
PBK is a serine/threonine kinase related to the dual specific mitogen-activated protein kinase kinase (MAPKK) family. Evidence suggests that mitotic phosphorylation is required for its catalytic activity. This mitotic kinase may be involved in the activation of lymphoid cells and support testicular functions, with a suggested role in the process of spermatogenesis. This genes encodes a serine/threonine kinase related to the dual specific mitogen-activated protein kinase kinase (MAPKK) family. Evidence suggests that mitotic phosphorylation is required for its catalytic activity. This mitotic kinase may be involved in the activation of lymphoid cells and support testicular functions, with a suggested role in the process of spermatogenesis. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Background References:
  • Uhl, G.R., (2008) Arch. Gen. Psychiatry 65 (6), 683-693.
Buffer:
Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Concentration:
batch dependent
Conjugate:
Unconjugated
Immunogen:
Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human PBK.
NCBI Gene ID #:
55872
NCBI Official Name:
PDZ binding kinase
NCBI Official Symbol:
PBK
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
36 kDa
Protein Accession #:
NP_060962
Protein GI Number:
18490991
Purification:
Antibody is purified by peptide affinity chromatography method.
Research Area:
Cell Cycle ,Cancer ,Signal Transduction
Swissprot #:
Q96KB5
User NOte:
Optimal dilutions for each application to be determined by the researcher.