WBP11 Antibody

ProSci
Product Code: PSI-26-115
Product Group: Primary Antibodies
Supplier: ProSci
CodeSizePrice
PSI-26-115-100ul100ul£662.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Rabbit
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
  • Human
  • Mouse
  • Rat
Applications:
  • Enzyme-Linked Immunosorbent Assay (ELISA)
  • Western Blot (WB)
Storage:
For short periods of storage (days) store at 4˚C. For longer periods of storage, store WBP11 antibody at -20˚C. As with any antibody avoid repeat freeze-thaw cycles.

Images

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Antibody used in WB on Human, Mouse at 2 ug/ml (Lane 1. Human NT-2 cells (60ug) lysate Lane 2. Mouse WT brain extract (80ug)).
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3 / 4
Antibody used in WB on Human Jurkat 1 ug/ml.
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Antibody used in WB on Human HeLa cells at 0.2-1 ug/ml.

Antibody used in WB on Human, Mouse at 2 ug/ml (Lane 1. Human NT-2 cells (60ug) lysate Lane 2. Mouse WT brain extract (80ug)).
Antibody used in WB on Human Jurkat 1 ug/ml.
Antibody used in WB on Human HeLa cells at 0.2-1 ug/ml.

Further Information

Additional Names:
WBP11, DKFZp779M1063, NPWBP, SIPP1, WBP-11
Application Note:
WBP11 antibody can be used for detection of WBP11 by ELISA at 1:12500. WBP11 antibody can be used for detection of WBP11 by western blot at 1 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
Background:
WBP11 is a nuclear protein, which colocalizes with mRNA splicing factors and intermediate filament-containing perinuclear networks. WBP11has 95% amino acid sequence identity to the mouse Wbp11 protein. It contains two proline-rich regions that bind to the WW domain of Npw38, a nuclear protein, and thus this protein is also called Npw38-binding protein NpwBP. The Npw38-NpwBP complex may function as a component of an mRNA factory in the nucleus.This gene encodes a nuclear protein, which colocalizes with mRNA splicing factors and intermediate filament-containing perinuclear networks. This protein has 95% amino acid sequence identity to the mouse Wbp11 protein. It contains two proline-rich regions that bind to the WW domain of Npw38, a nuclear protein, and thus this protein is also called Npw38-binding protein NpwBP. The Npw38-NpwBP complex may function as a component of an mRNA factory in the nucleus.
Background References:
  • Olsen, J.V., (2006) Cell 127 (3), 635-648.
Buffer:
Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Concentration:
batch dependent
Conjugate:
Unconjugated
Immunogen:
Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human WBP11.
NCBI Gene ID #:
51729
NCBI Official Name:
WW domain binding protein 11
NCBI Official Symbol:
WBP11
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
70 kDa
Protein Accession #:
NP_057396
Protein GI Number:
7706501
Purification:
Antibody is purified by peptide affinity chromatography method.
Research Area:
Immunology
Swissprot #:
Q9Y2W2
User NOte:
Optimal dilutions for each application to be determined by the researcher.