TL-1A Antibody
| Code | Size | Price |
|---|
| PSI-38-162-0.1mg | 0.1mg | £524.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Applications:
- Enzyme-Linked Immunosorbent Assay (ELISA)
- Western Blot (WB)
Storage:
TL-1A antibody is stable for at least 2 years from date of receipt at -20˚C. The reconstituted antibody is stable for at least two weeks at 2-8˚C. Frozen aliquots are stable for at least 6 months when stored at -20˚C. Avoid repeated freeze-
Documents
Further Information
Additional Names:
TL1, TL1A, VEGI, VEGI192A, TL1, Tumor necrosis factor ligand superfamily member 15, TNF ligand-related molecule 1,
Application Note:
ELISA:
Indirect:
To detect hTL-1A by indirect ELISA (using 100 μL/well antibody solution) a concentration of 0.5 - 2.0 μg/mL of this antibody is required. This antigen affinity purified antibody, in conjunction with compatible secondary reagents, allows the detection of at least 0.2 - 0.4 ng/well of recombinant hTL-1A.
Sandwich
To detect hTL-1A by sandwich ELISA (using 100 μL/well antibody solution) a concentration of 0.5 - 2.0 μg/mL of this antibody is required. This antigen affinity purified antibody, in conjunction with our biotinylated Anti-Human TL-1A as a detection antibody, allows the detection of at least 0.2 - 0.4 ng/well of recombinant hTL-1A.
Western Blot:
To detect hTL-1A by Western Blot analysis this antibody can be used at a concentration of 0.1 - 0.2 μg/mL. Used in conjunction with compatible secondary reagents the detection limit for recombinant hTL-1A is 1.5 - 3.0 ng/lane, under either reducing or non-reducing conditions
Indirect:
To detect hTL-1A by indirect ELISA (using 100 μL/well antibody solution) a concentration of 0.5 - 2.0 μg/mL of this antibody is required. This antigen affinity purified antibody, in conjunction with compatible secondary reagents, allows the detection of at least 0.2 - 0.4 ng/well of recombinant hTL-1A.
Sandwich
To detect hTL-1A by sandwich ELISA (using 100 μL/well antibody solution) a concentration of 0.5 - 2.0 μg/mL of this antibody is required. This antigen affinity purified antibody, in conjunction with our biotinylated Anti-Human TL-1A as a detection antibody, allows the detection of at least 0.2 - 0.4 ng/well of recombinant hTL-1A.
Western Blot:
To detect hTL-1A by Western Blot analysis this antibody can be used at a concentration of 0.1 - 0.2 μg/mL. Used in conjunction with compatible secondary reagents the detection limit for recombinant hTL-1A is 1.5 - 3.0 ng/lane, under either reducing or non-reducing conditions
Background:
TL1A is a cytokine that belongs to the tumor necrosis factor (TNF) ligand family. It is a TNF like ligand for DR3 and TR6/DcR3 and functions as a T cell costimulator. TL1A is abundantly expressed in endothelial cells, but is not expressed in either B or T cells. The expression of this protein is inducible by TNF and IL 1 alpha. TL1A can activate NF kappa B and MAP kinases, and acts as an autocrine factor to induce apoptosis in endothelial cells and may function as an angiogenesis inhibitor. TL1A is a longer variant of TL1.
Concentration:
batch dependent
Conjugate:
Unconjugated
Immunogen:
Produced from sera of rabbits pre-immunized with highly pure (>98%) recombinant hTL-1A. Human TL-1A specific antibody was purified by affinity chromatography employing immobilized hTL-1A matrix.
NCBI Gene ID #:
9966
NCBI Official Name:
tumor necrosis factor (ligand) superfamily, member 15
NCBI Official Symbol:
TNFSF15
NCBI Organism:
Homo sapiens
Physical State:
Lyophilized
Protein Accession #:
O95150
Protein GI Number:
189047102
Research Area:
Chemokines & Cytokines,Immunology,Antibody Pairs
Swissprot #:
O95150
User NOte:
Centrifuge vial prior to opening.