C21orf33 Antibody
| Code | Size | Price |
|---|
| PSI-30-121-100ul | 100ul | £609.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Applications:
- Enzyme-Linked Immunosorbent Assay (ELISA)
- Immunohistochemistry (IHC)
- Western Blot (WB)
Storage:
For short periods of storage (days) store at 4˚C. For longer periods of storage, store C21orf33 antibody at -20˚C. As with any antibody avoid repeat freeze-thaw cycles.
Documents
Further Information
Additional Names:
C21orf33, D21S2048E, ES1, GT335, HES1, KNP-I, KNPH, KNPI
Application Note:
C21orf33 antibody can be used for detection of C21orf33 by ELISA at 1:1562500. C21orf33 antibody can be used for detection of C21orf33 by western blot at 2.5 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
Background:
C21orf33 inhibits both estrogen- and heregulin-beta1-stimulated growth of breast cancer cells, and further suggests that growth inhibition induced in these cells by all-trans retinoic acid occurs via HES-1-mediated downregulation of E2F-1 expression. C21orf33 may also be a candidate protein involved in the pathogenesis of the brain deficit in DS.
Background References:
- Hartman, J., (2004) Oncogene 23 (54), 8826-8833.
Buffer:
Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Concentration:
batch dependent
Conjugate:
Unconjugated
Immunogen:
Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human C21orf33.
NCBI Gene ID #:
8209
NCBI Official Name:
chromosome 21 open reading frame 33
NCBI Official Symbol:
C21orf33
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
21 kDa, 28 kDa
Protein Accession #:
NP_937798
Protein GI Number:
296531408
Purification:
Antibody is purified by protein A chromatography method.
Research Area:
Cancer
Swissprot #:
P30042-2
User NOte:
Optimal dilutions for each application to be determined by the researcher.