CHST1 Antibody
| Code | Size | Price |
|---|
| PSI-30-071-100ul | 100ul | £609.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
- Canine (dog)
- Human
- Mouse
- Rat
Applications:
- Enzyme-Linked Immunosorbent Assay (ELISA)
- Immunohistochemistry (IHC)
- Western Blot (WB)
Storage:
For short periods of storage (days) store at 4˚C. For longer periods of storage, store CHST1 antibody at -20˚C. As with any antibody avoid repeat freeze-thaw cycles.
Documents
Further Information
Additional Names:
CHST1, C6ST, KS6ST, KSGal6ST, KSST, GST-1
Application Note:
CHST1 antibody can be used for detection of CHST1 by ELISA at 1:1562500. CHST1 antibody can be used for detection of CHST1 by western blot at 1.25 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
Background:
CHST1 catalyzes the transfer of sulfate to position 6 of galactose (Gal) residues of keratan. It has a preference for sulfating keratan sulfate, but it also transfers sulfate to the unsulfated polymer. The sulfotransferase activity on sialyl LacNAc structures is much higher than the corresponding desialylated substrate, and only internal Gal residues are sulfated. It may function in the sulfation of sialyl N-acetyllactosamine oligosaccharide chains attached to glycoproteins. It participates in biosynthesis of selectin ligands. Selectin ligands are present in high endothelial cells (HEVs) and play a central role in lymphocyte homing at sites of inflammation.
Background References:
- Yamada, T., Biochem. J. 384 (PT 3), 567-575 (2004).
Buffer:
Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Concentration:
batch dependent
Conjugate:
Unconjugated
Immunogen:
Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human CHST1.
NCBI Gene ID #:
8534
NCBI Official Name:
carbohydrate (keratan sulfate Gal-6) sulfotransferase 1
NCBI Official Symbol:
CHST1
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
47 kDa
Protein Accession #:
NP_003645
Protein GI Number:
4502841
Purification:
Antibody is purified by protein A chromatography method.
Research Area:
Membrane ,Signal Transduction
Swissprot #:
O43916
User NOte:
Optimal dilutions for each application to be determined by the researcher.