HAL Antibody
Code | Size | Price |
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PSI-30-098-100ul | 100ul | £609.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
- Human
- Mouse
- Rat
Applications:
- Enzyme-Linked Immunosorbent Assay (ELISA)
- Immunohistochemistry (IHC)
- Western Blot (WB)
Storage:
For short periods of storage (days) store at 4˚C. For longer periods of storage, store HAL antibody at -20˚C. As with any antibody avoid repeat freeze-thaw cycles.
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Further Information
Additional Names:
HAL, HIS, HSTD
Application Note:
HAL antibody can be used for detection of HAL by ELISA at 1:312500. HAL antibody can be used for detection of HAL by western blot at 1.25 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
Background:
HAL is a cytosolic enzyme catalyzing the first reaction in histidine catabolism, the nonoxidative deamination of L-histidine to trans-urocanic acid. HAL defects cause histidinemia which is characterized by increased histidine and histamine and decreased urocanic acid in body fluidsHistidine ammonia-lyase is a cytosolic enzyme catalyzing the first reaction in histidine catabolism, the nonoxidative deamination of L-histidine to trans-urocanic acid. Histidine ammonia-lyase defects cause histidinemia which is characterized by increased histidine and histamine and decreased urocanic acid in body fluids.
Background References:
- Aleman, G., Am. J. Physiol. Endocrinol. Metab. 289 (1), E172-E179 (2005).
Buffer:
Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Concentration:
batch dependent
Conjugate:
Unconjugated
Immunogen:
Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human HAL.
NCBI Gene ID #:
3034
NCBI Official Name:
histidine ammonia-lyase
NCBI Official Symbol:
HAL
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
72 kDa
Protein Accession #:
NP_002099
Protein GI Number:
4504333
Purification:
Antibody is purified by protein A chromatography method.
Swissprot #:
P42357
User NOte:
Optimal dilutions for each application to be determined by the researcher.