NR3C2 Antibody
| Code | Size | Price |
|---|
| PSI-30-075-100ul | 100ul | £609.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Applications:
- Enzyme-Linked Immunosorbent Assay (ELISA)
- Immunohistochemistry (IHC)
- Western Blot (WB)
Storage:
For short periods of storage (days) store at 4˚C. For longer periods of storage, store NR3C2 antibody at -20˚C. As with any antibody avoid repeat freeze-thaw cycles.
Documents
Further Information
Additional Names:
NR3C2, MCR, MGC133092, MLR, MR, NR3C2VIT
Application Note:
NR3C2 antibody can be used for detection of NR3C2 by ELISA at 1:312500. NR3C2 antibody can be used for detection of NR3C2 by western blot at 1.25 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
Background:
NR3C2 is a receptor for both mineralocorticoids (MC) such as aldosterone and glucocorticoids (GC) such as corticosterone or cortisol. It binds to mineralocorticoid response elements (MRE) and transactivates target genes. The effect of MC is to increase ion and water transport and thus raise extracellular fluid volume and blood pressure and lower potassium levels.
Background References:
- Liu, G., (2006) Biochem. Biophys. Res. Commun. 342 (4), 1291-1296.
Buffer:
Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Concentration:
batch dependent
Conjugate:
Unconjugated
Immunogen:
Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human NR3C2.
NCBI Gene ID #:
4306
NCBI Official Name:
nuclear receptor subfamily 3, group C, member 2
NCBI Official Symbol:
NR3C2
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
107 kDa
Protein Accession #:
NP_000892
Protein GI Number:
158508572
Purification:
Antibody is purified by protein A chromatography method.
Research Area:
Transcription ,Cancer ,Signal Transduction
Swissprot #:
P08235
User NOte:
Optimal dilutions for each application to be determined by the researcher.