PTCH1 Antibody
| Code | Size | Price |
|---|
| PSI-29-972-100ul | 100ul | £662.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
- Human
- Mouse
- Rat
Applications:
- Enzyme-Linked Immunosorbent Assay (ELISA)
- Western Blot (WB)
Storage:
For short periods of storage (days) store at 4˚C. For longer periods of storage, store PTCH1 antibody at -20˚C. As with any antibody avoid repeat freeze-thaw cycles.
Documents
Further Information
Additional Names:
PTCH1, PTC, BCNS, HPE7, PTC1, PTCH, NBCCS, PTCH11
Application Note:
PTCH1 antibody can be used for detection of PTCH1 by ELISA at 1:312500. PTCH1 antibody can be used for detection of PTCH1 by western blot at 0.25 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
Background:
PTCH1 is a member of the patched gene family. The protein is the receptor for sonic hedgehog, a secreted molecule implicated in the formation of embryonic structures and in tumorigenesis. It functions as a tumor suppressor. Mutations of its gene have been associated with nevoid basal cell carcinoma syndrome, esophageal squamous cell carcinoma, trichoepitheliomas, transitional cell carcinomas of the bladder, as well as holoprosencephaly.
Buffer:
Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Concentration:
batch dependent
Conjugate:
Unconjugated
Immunogen:
Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human PTCH1.
NCBI Gene ID #:
5727
NCBI Official Name:
patched 1
NCBI Official Symbol:
PTCH1
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
37 kDa, 161 kDa, 154 kDa, 161 kDa, 144 kDa, 144 kDa, 144 kDa, 144 kDa
Protein Accession #:
AAR21240
Protein GI Number:
38489136
Purification:
Antibody is purified by peptide affinity chromatography method.
Research Area:
Membrane ,Cancer
Swissprot #:
Q6TKP8
User NOte:
Optimal dilutions for each application to be determined by the researcher.