RNF40 Antibody
| Code | Size | Price |
|---|
| PSI-29-844-100ul | 100ul | £609.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
- Canine (dog)
- Human
- Mouse
- Rat
Applications:
- Enzyme-Linked Immunosorbent Assay (ELISA)
- Immunohistochemistry (IHC)
- Western Blot (WB)
Storage:
For short periods of storage (days) store at 4˚C. For longer periods of storage, store RNF40 antibody at -20˚C. As with any antibody avoid repeat freeze-thaw cycles.
Documents
Further Information
Additional Names:
RNF40, BRE1B, DKFZp686K191, KIAA0661, MGC13051, RBP95, STARING
Application Note:
RNF40 antibody can be used for detection of RNF40 by ELISA at 1:312500. RNF40 antibody can be used for detection of RNF40 by western blot at 1.25 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
Background:
RNF40 contains a RING finger, a motif known to be involved in protein-protein and protein-DNA interactions. This protein was reported to interact with the tumor suppressor protein RB1. Studies of the rat counterpart suggested that this protein may function as an E3 ubiquitin-protein ligase, and facilitate the ubiquitination and degradation of syntaxin 1, which is an essential component of the neurotransmitter release machinery.The protein encoded by this gene contains a RING finger, a motif known to be involved in protein-protein and protein-DNA interactions. This protein was reported to interact with the tumor suppressor protein RB1. Studies of the rat counterpart suggested that this protein may function as an E3 ubiquitin-protein ligase, and facilitate the ubiquitination and degradation of syntaxin 1, which is an essential component of the neurotransmitter release machinery.
Background References:
- Zhu, B., (2005) Mol. Cell 20 (4), 601-611.
Buffer:
Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Concentration:
batch dependent
Conjugate:
Unconjugated
Immunogen:
Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human RNF40.
NCBI Gene ID #:
9810
NCBI Official Name:
ring finger protein 40, E3 ubiquitin protein ligase
NCBI Official Symbol:
RNF40
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
114 kDa
Protein Accession #:
NP_055586
Protein GI Number:
7662230
Purification:
Antibody is purified by protein A chromatography method.
Research Area:
Cancer ,Apoptosis ,Homeostasis
Swissprot #:
O75150
User NOte:
Optimal dilutions for each application to be determined by the researcher.