RORA Antibody
| Code | Size | Price |
|---|
| PSI-30-078-100ul | 100ul | £609.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
- Canine (dog)
- Human
- Mouse
- Rat
Applications:
- Enzyme-Linked Immunosorbent Assay (ELISA)
- Western Blot (WB)
Storage:
For short periods of storage (days) store at 4˚C. For longer periods of storage, store RORA antibody at -20˚C. As with any antibody avoid repeat freeze-thaw cycles.
Documents
Further Information
Additional Names:
RORA, MGC119326, MGC119329, NR1F1, ROR1, ROR2, ROR3, RZRA, RZR-ALPHA
Application Note:
RORA antibody can be used for detection of RORA by ELISA at 1:312500. RORA antibody can be used for detection of RORA by western blot at 1.25 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
Background:
The protein encoded by RORA is a member of the NR1 subfamily of nuclear hormone receptors. It can bind as a monomer or as a homodimer to hormone response elements upstream of several genes to enhance the expression of those genes. The specific functions of this protein are not known, but it has been shown to interact with NM23-2, a nucleoside diphosphate kinase involved in organogenesis and differentiation, as well as with NM23-1, the product of a tumor metastasis suppressor candidate gene.The protein encoded by this gene is a member of the NR1 subfamily of nuclear hormone receptors. It can bind as a monomer or as a homodimer to hormone response elements upstream of several genes to enhance the expression of those genes. The specific functions of this protein are not known, but it has been shown to interact with NM23-2, a nucleoside diphosphate kinase involved in organogenesis and differentiation, as well as with NM23-1, the product of a tumor metastasis suppressor candidate gene. Four transcript variants encoding different isoforms have been described for this gene.
Background References:
- Boukhtouche, F., (2006) J. Neurochem. 96 (6), 1778-1789.
Buffer:
Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Concentration:
batch dependent
Conjugate:
Unconjugated
Immunogen:
Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human RORA.
NCBI Gene ID #:
6095
NCBI Official Name:
RAR-related orphan receptor A
NCBI Official Symbol:
RORA
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
62 kDa, 63 kDa, 59 kDa, 54 kDa
Protein Accession #:
NP_002934
Protein GI Number:
4506577
Purification:
Antibody is purified by protein A chromatography method.
Research Area:
Transcription ,Cancer ,Signal Transduction
Swissprot #:
P35398-3
User NOte:
Optimal dilutions for each application to be determined by the researcher.