YWHAZ Antibody
| Code | Size | Price |
|---|
| PSI-30-349-100ul | 100ul | £609.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
- Canine (dog)
- Human
- Mouse
- Rat
Applications:
- Enzyme-Linked Immunosorbent Assay (ELISA)
- Western Blot (WB)
Storage:
For short periods of storage (days) store at 4˚C. For longer periods of storage, store YWHAZ antibody at -20˚C. As with any antibody avoid repeat freeze-thaw cycles.
Documents
Further Information
Additional Names:
YWHAZ, KCIP-1, MGC111427, MGC126532, MGC138156, HEL4, YWHAD, HEL-S-3, 14-3-3-zeta
Application Note:
YWHAZ antibody can be used for detection of YWHAZ by ELISA at 1:62500. YWHAZ antibody can be used for detection of YWHAZ by western blot at 5.0 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
Background:
YWHAZ belongs to the 14-3-3 family of proteins which mediate signal transduction by binding to phosphoserine-containing proteins. This highly conserved protein family is found in both plants and mammals, and this protein is 99% identical to the mouse, rat and sheep orthologs. The protein interacts with IRS1 protein, suggesting a role in regulating insulin sensitivity.This gene product belongs to the 14-3-3 family of proteins which mediate signal transduction by binding to phosphoserine-containing proteins. This highly conserved protein family is found in both plants and mammals, and this protein is 99% identical to the mouse, rat and sheep orthologs. The encoded protein interacts with IRS1 protein, suggesting a role in regulating insulin sensitivity. Two transcript variants differing in the 5' UTR, but encoding the same protein, have been identified for this gene.
Background References:
- Coblitz, B., (2005) J. Biol. Chem. 280 (43), 36263-36272.
Buffer:
Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Concentration:
batch dependent
Conjugate:
Unconjugated
Immunogen:
Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human YWHAZ.
NCBI Gene ID #:
7534
NCBI Official Name:
tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta
NCBI Official Symbol:
YWHAZ
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
28 kDa, 28 kDa
Protein Accession #:
NP_003397
Protein GI Number:
4507953
Purification:
Antibody is purified by protein A chromatography method.
Research Area:
Cancer
Swissprot #:
P63104
User NOte:
Optimal dilutions for each application to be determined by the researcher.