BIM Antibody
| Code | Size | Price |
|---|
| PSI-79-398-0.1mg | 0.1mg | £481.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
- Human
- Mouse
- Rat
Applications:
- Immunohistochemistry (IHC)
- Western Blot (WB)
Storage:
Store antibody at -20˚C for up to one year.
Documents
Further Information
Additional Names:
BAM, BIM, BOD, GLNS, BCL2-like protein 11, BCL2L11, Bcl-2 related ovarian death protein,
Application Note:
Western Blot: 1:500~1:1000, Immunohistochemistry: 1:50~1:100
Background:
Induces apoptosis. Isoform BimL is more potent than isoform BimEL. Isoform Bim-alpha1, isoform Bim-alpha2 and isoform Bim-alpha3 induce apoptosis, although less potent than the isoforms BimEL, BimL and BimS. Isoform Bim-gamma induces apoptosis.
Background References:
- Fukazawa H, et al. (2004) Mol Cancer Ther ; 3 (10): 1281-1288Luciano F, et al. (2003) Oncogene ; 22 (43): 6785-6793
Buffer:
Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Concentration:
1 mg/mL
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
BIM (Ab-69) antibody was raised against a peptide sequence around aa.67~71 (P-A-S-P-G) derived from Human BIM.
NCBI Gene ID #:
10018
NCBI Official Name:
BCL2-like 11 (apoptosis facilitator)
NCBI Official Symbol:
BCL2L11
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
23 kDa
Protein Accession #:
NP_006529.1
Protein GI Number:
5729740
Purification:
Antibodies were purified by affinity-chromatography using epitope-specific peptide.
Research Area:
Apoptosis,Cancer
SPECIFICITY:
This antibody detects endogenous level of total BIM protein.
Swissprot #:
O43521