CaMKII Antibody
| Code | Size | Price |
|---|
| PSI-79-492-0.1mg | 0.1mg | £488.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
- Human
- Mouse
- Rat
Application: Western Blot (WB)
Storage:
Store antibody at -20˚C for up to one year.
Documents
Further Information
Additional Names:
CaMKII, R74975, mKIAA0968, FNRB, MDF2, MSK12, CAMK2A, CaMKII-alpha
Application Note:
Western Blot: 1:500~1:1000
Background:
CaM-kinase II (CAMK2) is a prominent kinase in the central nervous system that may function in long-term potentiation and neurotransmitter release. Member of the NMDAR signaling complex in excitatory synapses it may regulate NMDAR-dependent potentiation of the AMPAR and synaptic plasticity .
Background References:
- Pak JH, et al. Proc Natl Acad Sci U S A. 2000 Oct 10; 97 (21): 11232-11237 Hudmon A, et al. J Cell Biol. Author manuscript; available in PMC 2006 May 7Miller P, et al. PLoS Biol. 2005 Apr; 3 (4): e107Runyan JD, et al. Learn Mem. 2005 Mar; 12 (2): 103-110.
Buffer:
Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Concentration:
1 mg/mL
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
CaMKII (Phospho-Thr286) antibody was raised against a peptide sequence around phosphorylation site of threonine 286 (Q-E-T (p) -V-D) derived from Human CaMKII.
Modifications:
Phospho-Specific
NCBI Gene ID #:
12322
NCBI Official Name:
calcium/calmodulin-dependent protein kinase II alpha
NCBI Official Symbol:
Camk2a
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
50 kDa
Protein Accession #:
NP_001273738.1
Protein GI Number:
558472775
Purification:
Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy using non-phosphopeptide.
Research Area:
Phospho-Specific,Neuroscience
SPECIFICITY:
This antibody detects endogenous level of CaMKII only when phosphorylated at threonine 286.
Swissprot #:
P11798