Connexin 43 Antibody

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ProSci
Product Code: PSI-79-383
Product Group: Primary Antibodies
Supplier: ProSci
CodeSizePrice
PSI-79-383-0.1mg0.1mg£481.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Rabbit
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
  • Human
  • Mouse
  • Rat
Applications:
  • Immunohistochemistry (IHC)
  • Western Blot (WB)
Storage:
Store antibody at -20˚C for up to one year.

Images

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Western blot analysis of lysed extracts from HT29 and HepG2 cells using Connexin 43 (Ab-367).
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Immunohistochemical analysis of paraffin-embedded human breast carcinoma tissue using Connexin 43 (Ab-367).
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Western blot analysis of lysed extracts from HT29 and HepG2 cells using Connexin 43 (Ab-367).
Immunohistochemical analysis of paraffin-embedded human breast carcinoma tissue using Connexin 43 (Ab-367).

Documents

Further Information

Additional Names:
HSS, CMDR, CX43, GJAL, ODDD, AVSD3, HLHS1, DFNB38, GLUT4, CXA1, CXN-43, Connexin 43, GJA1
Application Note:
Western Blot: 1:500~1:1000, Immunohistochemistry: 1:50~1:100
Background:
One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell. May play a critical role in the physiology of hearing by participating in the recycling of potassium to the cochlear endolymph.
Background References:
  • Joell L. Solan1, et al. (2003) Cell Science 116: 2203-2211Satoshi Matsushita, et al. (2006) Histochemistry and Cytochemistry 54 (3): 343-353, Xiaoyong Bao, et al. (2004) Cell Physiol 286: C647-C654W. E. I. Li, et al. (1998) European Journal of Neuroscience 10: 2444
Buffer:
Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Concentration:
1 mg/mL
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
Connexin 43 (Ab-367) antibody was raised against a peptide sequence around aa. 365~369 (R-A-S-S-R) derived from Human Connexin 43.
NCBI Gene ID #:
2697
NCBI Official Name:
gap junction protein, alpha 1, 43kDa
NCBI Official Symbol:
GJA1
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
43 kDa
Protein Accession #:
NP_000156.1
Protein GI Number:
4504001
Purification:
Antibodies were purified by affinity-chromatography using epitope-specific peptide.
Research Area:
Other
SPECIFICITY:
This antibody detects endogenous level of total Connexin43 protein.
Swissprot #:
P17302