Cyclin E1 Antibody
| Code | Size | Price |
|---|
| PSI-79-510-0.1mg | 0.1mg | £488.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Application: Western Blot (WB)
Storage:
Store antibody at -20˚C for up to one year.
Documents
Further Information
Additional Names:
CCNE, SIGLEC2, CCNE, CCNE1
Application Note:
Western Blot: 1:1000
Background:
The protein encoded by this gene belongs to the highly conserved cyclin family, whose members are characterized by a dramatic periodicity in protein abundance through the cell cycle. Cyclins function as regulators of CDK kinases. Different cyclins exhibit distinct expression and degradation patterns which contribute to the temporal coordination of each mitotic event. This cyclin forms a complex with and functions as a regulatory subunit of CDK2, whose activity is required for cell cycle G1/S transition.
Background References:
- Won K. A., Reed S. I. EMBO J. 15:4182-4193 (1996) Welcker M., Singer J., Loeb K. R., Grim J., Bloecher A., Mol. Cell 12:381-392 (2003)
Buffer:
Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Concentration:
1 mg/mL
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
Cyclin E1 (phospho-Thr395) antibody was raised against a peptide sequence around phosphorylation site of threonine 395 (L-L-T (p) -P-P) derived from Human Cyclin E1.
Modifications:
Phospho-Specific
NCBI Gene ID #:
898
NCBI Official Name:
cyclin E1
NCBI Official Symbol:
CCNE1
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
48 kDa
Protein Accession #:
NP_001229.1
Protein GI Number:
17318559
Purification:
Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy using non-phosphopeptide.
Research Area:
Phospho-Specific,Cell Cycle
SPECIFICITY:
This antibody detects endogenous level of Cyclin E1 only when phosphorylated at threonine 395.
Swissprot #:
P24864