Ephrin-B2 Antibody
| Code | Size | Price |
|---|
| PSI-79-465-0.1mg | 0.1mg | £488.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
- Human
- Mouse
Application: Western Blot (WB)
Storage:
Store antibody at -20˚C for up to one year.
Documents
Further Information
Additional Names:
HTKL, EPLG5, Htk-L, LERK5, MEK1, PRKMK1, HTKL
Application Note:
Western Blot: 1:500~1:1000
Background:
This gene product belongs to the 14-3-3 family of proteins which mediate signal transduction by binding to phosphoserine-containing proteins. This highly conserved protein family is found in both plants and mammals, and this protein is 99% identical to the mouse, rat and sheep orthologs. The encoded protein interacts with IRS1 protein, suggesting a role in regulating insulin sensitivity. Several transcript variants that differ in the 5' UTR but that encode the same protein have been identified for this gene.
Background References:
- Chrencik JE, et al. ( 2006) J Biol Chem;281 (38): 28185-28192. Kertesz N, et al. ( 2006) Blood;107 (6): 2330-2338. Noren NK, et al. ( 2004) Proc Natl Acad Sci USA;101 (15): 5583-5588
Buffer:
Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Concentration:
1 mg/mL
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
Ephrin-B2 (Phospho-Tyr316) antibody was raised against a peptide sequence around phosphorylation site of tyrosine 316 (P-V-Y (p) -I-V) derived from Human Ephrin-B2.
Modifications:
Phospho-Specific
NCBI Gene ID #:
1948
NCBI Official Name:
ephrin-B2
NCBI Official Symbol:
EFNB2
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
37 kDa
Protein Accession #:
NP_004084.1
Protein GI Number:
4758250
Purification:
Antibodies were purified by affinity-chromatography using epitope-specific peptide.
Research Area:
Phospho-Specific,Apoptosis,Cancer,Cell Cycle
SPECIFICITY:
This antibody detects endogenous levels of Ephrin-B2 only when phosphorylated at tyrosine 316.
Swissprot #:
P52799