ERAB Antibody
| Code | Size | Price |
|---|
| PSI-79-705-0.1mg | 0.1mg | £481.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
- Human
- Mouse
- Rat
Application: Western Blot (WB)
Storage:
Store antibody at -20˚C for up to one year.
Documents
Further Information
Additional Names:
ABAD, CAMR, ERAB, HCD2, MHBD, HADH2, MRPP2, MRX17, MRX31, SCHAD, MRXS10, SDR5C1, 17b-HSD10, DUPXp11.22, ABAD
Application Note:
Western Blot: 1:500~1:1000
Background:
Functions in mitochondrial tRNA maturation. Part of mitochondrial ribonuclease P, an enzyme composed of MRPP1/RG9MTD1, MRPP2/HSD17B10 and MRPP3/KIAA0391, which cleaves tRNA molecules in their 5'-ends. By interacting with intracellular amyloid-beta, it may contribute to the neuronal dysfunction associated with Alzheimer disease (AD).
Background References:
- Holzmann J., Frank P., Loeffler E., Bennett K. L., Gerner C., Rossmanith W. Cell 135:462-474 (2008)
Buffer:
Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Concentration:
1 mg/mL
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
ERAB antibody was raised against a peptide sequence around aa.253~257 (L-D-G-A-I) derived from Human ERAB.
NCBI Gene ID #:
3028
NCBI Official Name:
hydroxysteroid (17-beta) dehydrogenase 10
NCBI Official Symbol:
HSD17B10
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
27 kDa
Protein Accession #:
NP_004484.1
Protein GI Number:
4758504
Purification:
Antibodies were purified by affinity-chromatography using epitope-specific peptide.
Research Area:
Neuroscience
SPECIFICITY:
This antibody detects endogenous level of total ERAB protein.
Swissprot #:
Q99714