Gab1 Antibody
| Code | Size | Price |
|---|
| PSI-79-606-0.1mg | 0.1mg | £481.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
- Human
- Rat
Application: Western Blot (WB)
Storage:
Store antibody at -20˚C for up to one year.
Documents
Further Information
Additional Names:
Growth factor receptor bound protein 2-associated protein 1
Application Note:
Western Blot: 1:500~1:1000
Background:
The protein encoded by Gab1 is a member of the IRS1-like multisubstrate docking protein family. It is an important mediator of branching tubulogenesis and plays a central role in cellular growth response, transformation and apoptosis. Two transcript variants encoding different isoforms have been found for this gene.
Background References:
- Anders Kallin, et al. (2004) J. Biol. Chem; 279: 17897 - 17904. Hideto Kameda, et al. (2001) Cell Growth Differ; 12: 307. Masaki Osawa, et al. (2002) J. Cell Biol; 158: 773.
Buffer:
Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Concentration:
1 mg/mL
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
Gab1 (Ab-627) antibody was raised against a peptide sequence around aa.625~629 (V-E-Y-L-D) derived from Human Gab1.
NCBI Gene ID #:
2549
NCBI Official Name:
GRB2-associated binding protein 1
NCBI Official Symbol:
GAB1
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
110 kDa
Protein Accession #:
NP_002030.2
Protein GI Number:
46370073
Purification:
Antibodies were purified by affinity-chromatography using epitope-specific peptide.
Research Area:
Other
SPECIFICITY:
This antibody detects endogenous level of total Gab1 protein.
Swissprot #:
Q13480