GABRB1 Antibody
| Code | Size | Price |
|---|
| PSI-79-582-0.1mg | 0.1mg | £481.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
- Human
- Mouse
- Rat
Application: Western Blot (WB)
Storage:
Store antibody at -20˚C for up to one year.
Documents
Further Information
Additional Names:
GABA(A) receptor, GABA(A)R beta-1, GBRB1, GABA-RB
Application Note:
Western Blot: 1:500~1:1000
Background:
The gamma-aminobutyric acid (GABA) A receptor is a multisubunit chloride channel that mediates the fastest inhibitory synaptic transmission in the central nervous system. This gene encodes GABA A receptor, beta 1 subunit. It is mapped to chromosome 4p12 in a cluster comprised of genes encoding alpha 4, alpha 2 and gamma 1 subunits of the GABA A receptor. Alteration of this gene is implicated in the pathogenetics of schizophrenia.
Background References:
- Collins AL, et al. (2006) Neurogenetics ;7 (3): 167-174. Ma DQ, et al. (2005) Am J Hum Genet ;77 (3): 377-388. Edenberg HJ, et al. (2004) Am J Hum Genet ;74 (4): 705-714.
Buffer:
Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Concentration:
1 mg/mL
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
GABRB1 (Ab-434) antibody was raised against a peptide sequence around aa.432~436 (R-A-S-Q-L) derived from Human GABRB1.
NCBI Gene ID #:
2560
NCBI Official Name:
gamma-aminobutyric acid (GABA) A receptor, beta 1
NCBI Official Symbol:
GABRB1
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
54 kDa
Protein Accession #:
NP_000803.2
Protein GI Number:
194097327
Purification:
Antibodies were purified by affinity-chromatography using epitope-specific peptide.
Research Area:
Neuroscience
SPECIFICITY:
This antibody detects endogenous level of total GABRB1 protein.
Swissprot #:
P18505