GluR1 Antibody
| Code | Size | Price |
|---|
| PSI-79-484-0.1mg | 0.1mg | £488.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
- Human
- Mouse
- Rat
Application: Western Blot (WB)
Storage:
Store antibody at -20˚C for up to one year.
Documents
Further Information
Additional Names:
GLUH1, GLUR1, GLURA, GluA1, HBGR1, Mtapt, Tau, GLR1, GLUH1, GRIA1, GluR-1, GluR-A
Application Note:
Western Blot: 1:500~1:1000
Background:
Glutamate receptors are the predominant excitatory neurotransmitter receptors in the mammalian brain and are activated in a variety of normal neurophysiologic processes. These receptors are heteromeric protein complexes with multiple subunits, each possessing transmembrane regions, and all arranged to form a ligand-gated ion channel. The classification of glutamate receptors is based on their activation by different pharmacologic agonists. This gene belongs to a family of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate (AMPA) receptors. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
Background References:
- Emamian ES, et al. (2004) J Neurosci. 24 (7): 1561-4Palmer, C. L. et al. (2005) Pharmacol. Rev. 57, 253-277.
Buffer:
Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Concentration:
1 mg/mL
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
GluR1 (phospho-Ser849) antibody was raised against a peptide sequence around phosphorylation site of serine 849 (Q-Q-S (p) -I-N ) derived from Human GluR1.
Modifications:
Phospho-Specific
NCBI Gene ID #:
2890
NCBI Official Name:
glutamate receptor, ionotropic, AMPA 1
NCBI Official Symbol:
GRIA1
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
110 kDa
Protein Accession #:
NP_000818.2
Protein GI Number:
167001419
Purification:
Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy using non-phosphopeptide.
Research Area:
Phospho-Specific,Neuroscience
SPECIFICITY:
This antibody detects endogenous level of GluR1 only when phosphorylated at serine 849.
Swissprot #:
P42261