HER2 Antibody

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ProSci
Product Code: PSI-79-307
Product Group: Primary Antibodies
Supplier: ProSci
CodeSizePrice
PSI-79-307-0.1mg0.1mg£481.00
Quantity:
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Overview

Host Type: Rabbit
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Applications:
  • Immunohistochemistry (IHC)
  • Western Blot (WB)
Storage:
Store antibody at -20˚C for up to one year.

Images

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Western blot analysis of lysed extracts from SKOV3 cells using HER2 (Ab-877).
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Immunohistochemical analysis of paraffin-embedded human breast carcinoma tissue using HER2 (Ab-877).
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Western blot analysis of lysed extracts from SKOV3 cells using HER2 (Ab-877).
Immunohistochemical analysis of paraffin-embedded human breast carcinoma tissue using HER2 (Ab-877).

Documents

Further Information

Additional Names:
NEU, NGL, HER2, TKR1, CD340, HER-2, MLN19, HER-2/neu, KIAA0288, C-erbB-2, ErbB2
Application Note:
Western Blot: 1:500~1:1000, Immunohistochemistry: 1:50~1:100
Background:
Essential component of a neuregulin-receptor complex, although neuregulins do not interact with it alone. GP30 is a potential ligand for this receptor. Not activated by EGF, TGF-alpha and amphiregulin.
Background References:
  • Dittadi, R. et al. (2000) J. Natl. Cancer Inst. 92, 1443-1444. Muthuswamy, S. K. et al. (1999) Mol. Cell. Biol. 19, 6845-6857. Qian, X. et al. (1994) Proc. Natl. Acad. Sci. USA 91, 1500-1504. Kwon, Y. K. et al. (1997) J. Neurosci. 17, 8293-8299. Klapper, L. N. et al. (2000) Cancer Res. 60, 3384-3388.
Buffer:
Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Concentration:
1 mg/mL
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
HER2 (Ab-877) antibody was raised against a peptide sequence around aa.875~879 (T-E-Y-H-A) derived from Human HER2.
NCBI Gene ID #:
2064
NCBI Official Name:
v-erb-b2 avian erythroblastic leukemia viral oncogene homolog 2
NCBI Official Symbol:
ERBB2
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
185 kDa
Protein Accession #:
NP_001005862.1
Protein GI Number:
54792098
Purification:
Antibodies were purified by affinity-chromatography using epitope-specific peptide.
Research Area:
Other
SPECIFICITY:
This antibody detects endogenous level of total HER2 protein.
Swissprot #:
P04626