IGF-1R Antibody

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ProSci
Product Code: PSI-79-316
Product Group: Primary Antibodies
Supplier: ProSci
CodeSizePrice
PSI-79-316-0.1mg0.1mg£481.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Rabbit
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
  • Human
  • Mouse
  • Rat
Applications:
  • Immunofluorescence (IF)
  • Immunohistochemistry (IHC)
  • Western Blot (WB)
Storage:
Store antibody at -20˚C for up to one year.

Images

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Western blot analysis of lysed extracts from 293 cells using IGF-1R (Ab-1161).
2 / 2
<b>Top Image:</b> Immunohistochemical analysis of paraffin-embedded human breast carcinoma tissue using IGF-1R (Ab-1161).<b>Bottom Image:</b> Immunofluorescence staining of methanol-fixed MCF cells using IGF-1R (Ab-1161).
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Western blot analysis of lysed extracts from 293 cells using IGF-1R (Ab-1161).
<b>Top Image:</b> Immunohistochemical analysis of paraffin-embedded human breast carcinoma tissue using IGF-1R (Ab-1161).<b>Bottom Image:</b> Immunofluorescence staining of methanol-fixed MCF cells using IGF-1R (Ab-1161).

Documents

Further Information

Additional Names:
IGFR, CD221, IGFIR, JTK13, MACS, PRKCSL, Insulin-like growth factor I receptor, IGF1R, kinase IGF1R
Application Note:
Western Blot: 1:500~1:1000, Immunohistochemistry: 1:50~1:100, Immunofluorescence: 1:100~1:200
Background:
This receptor binds insulin-like growth factor 1 (IGF1) with a high affinity and IGF2 with a lower affinity. It has a tyrosine-protein kinase activity, which is necessary for the activation of the IGF1-stimulated downstream signaling cascade. When present in a hybrid receptor with INSR, binds IGF1.
Background References:
  • Li S, et al. (1994) J Biol Chem; 269 (51) . Hernandez-Sanchez C, et al. (1995) J Biol Chem.
Buffer:
Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Concentration:
1 mg/mL
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
IGF-1R (Ab-1161) antibody was raised against a peptide sequence around aa.1159~1163 (D-I-Y-E-T) derived from Human IGF-1R .
NCBI Gene ID #:
3480
NCBI Official Name:
insulin-like growth factor 1 receptor
NCBI Official Symbol:
IGF1R
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
200 95 kDa
Protein Accession #:
NP_000866.1
Protein GI Number:
4557665
Purification:
Antibodies were purified by affinity-chromatography using epitope-specific peptide.
Research Area:
Other
SPECIFICITY:
This antibody detects endogenous level of total IGF-1R protein.
Swissprot #:
P08069