IGF-1R Antibody
| Code | Size | Price |
|---|
| PSI-79-528-0.1mg | 0.1mg | £481.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
- Human
- Mouse
- Rat
Application: Western Blot (WB)
Storage:
Store antibody at -20˚C for up to one year.
Documents
Further Information
Additional Names:
IGFR, CD221, IGFIR, JTK13, Insulin-like growth factor I receptor, IGF1R, kinase IGF1R
Application Note:
Western Blot: 1:500~1:1000
Background:
This receptor binds insulin-like growth factor 1 (IGF1) with a high affinity and IGF2 with a lower affinity. It has a tyrosine-protein kinase activity, which is necessary for the activation of the IGF1-stimulated downstream signaling cascade. When present in a hybrid receptor with INSR, binds IGF1.
Background References:
- Li S, et al. (1994) J Biol Chem; 269 (51): 32558-64.
Buffer:
Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Concentration:
1 mg/mL
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
IGF-1R (Ab-1165/1166) antibody was raised against a peptide sequence around aa.1163~1167/1164~1168 (T-D-Y-Y-R-K) derived from Human IGF-1R .
NCBI Gene ID #:
3480
NCBI Official Name:
insulin-like growth factor 1 receptor
NCBI Official Symbol:
IGF1R
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
200, 95 kDa
Protein Accession #:
NP_000866.1
Protein GI Number:
4557665
Purification:
Antibodies were purified by affinity-chromatography using epitope-specific peptide.
Research Area:
Other
SPECIFICITY:
This antibody detects endogenous level of total IGF-1R protein.
Swissprot #:
P08069