MCL1 Antibody
| Code | Size | Price |
|---|
| PSI-79-656-0.1mg | 0.1mg | £481.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Application: Western Blot (WB)
Storage:
Store antibody at -20˚C for up to one year.
Documents
Further Information
Additional Names:
TM, EAT, MCL1L, MCL1S, Mcl-1, BCL2L3, MCL1-ES, bcl2-L-3, mcl1/EAT, TUBB4, TM
Application Note:
Western Blot: 1:500~1:1000
Background:
Involved in the regulation of apoptosis versus cell survival, and in the maintenance of viability but not of proliferation. Mediates its effects by interactions with a number of other regulators of apoptosis. Isoform 1 inhibits apoptosis. Isoform 2 promotes apoptosis.
Background References:
- Bingle C. D., Craig R. W., Swales B. M., Singleton V., Zhou P., Whyle M. K. B. J. Biol. Chem. 275:22136-22146 (2000)
Buffer:
Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Concentration:
1 mg/mL
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
MCL1 antibody was raised against a peptide sequence around aa.148~152 (N-N-T-S-T) derived from Human MCL1.
NCBI Gene ID #:
4170
NCBI Official Name:
myeloid cell leukemia sequence 1 (BCL2-related)
NCBI Official Symbol:
MCL1
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
42 kDa
Protein Accession #:
NP_068779.1
Protein GI Number:
11386165
Purification:
Antibodies were purified by affinity-chromatography using epitope-specific peptide.
Research Area:
Apoptosis
SPECIFICITY:
This antibody detects endogenous level of total MCL1 protein.
Swissprot #:
Q07820