MELK Antibody

ProSci
Product Code: PSI-79-727
Product Group: Primary Antibodies
Supplier: ProSci
CodeSizePrice
PSI-79-727-0.1mg0.1mg£481.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Rabbit
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
  • Human
  • Mouse
  • Rat
Application: Western Blot (WB)
Storage:
Store antibody at -20˚C for up to one year.

Images

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Western blot analysis of extract from Rat brain tissue using MELK Antibody.

Western blot analysis of extract from Rat brain tissue using MELK Antibody.

Further Information

Additional Names:
HPK38, hPK38, KIAA0175, hMELK
Application Note:
Western Blot: 1:500
Background:
Phosphorylates ZNF622 and may contribute to its redirection to the nucleus. May be involved in the inhibition of spliceosome assembly during mitosis.
Background References:
  • Seong H. -A., Gil M., Kim K. -T., Kim S. -J., Ha H. Biochem. J. 361:597-604 (2002) Vulsteke V., Beullens M., Boudrez A., Keppens S., Van Eynde A., Rider M. H., Stalmans W., Bollen M. J. Biol. Chem. 279:8642-8647 (2004)
Buffer:
Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Concentration:
1 mg/mL
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
MELK antibody was raised against a peptide sequence around aa.626~630 (I-R-R-Q-R) derived from Human MELK.
NCBI Gene ID #:
9833
NCBI Official Name:
maternal embryonic leucine zipper kinase
NCBI Official Symbol:
MELK
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
74 kDa
Protein Accession #:
NP_055606.1
Protein GI Number:
7661974
Purification:
Antibodies were purified by affinity-chromatography using epitope-specific peptide.
Research Area:
Neuroscience,Stem Cell
SPECIFICITY:
This antibody detects endogenous level of total MELK protein.
Swissprot #:
Q14680