N-Cadherin Antibody

ProSci
Product Code: PSI-79-671
Product Group: Primary Antibodies
Supplier: ProSci
CodeSizePrice
PSI-79-671-0.1mg0.1mg£481.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Rabbit
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
  • Human
  • Mouse
  • Rat
Application: Western Blot (WB)
Storage:
Store antibody at -20˚C for up to one year.

Images

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Western blot analysis of extract from HT29 cells using N-Cadherin (CD325).

Western blot analysis of extract from HT29 cells using N-Cadherin (CD325).

Further Information

Additional Names:
CDHN, NCAD, CD325, CDw325, CDH2, CDCN
Application Note:
Western Blot: 1:500
Background:
Cadherins are calcium dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell types. CDH2 may be involved in neuronal recognition mechanism. In hippocampal neurons, may regulate dendritic spine density
Background References:
  • Bhatt A. S. et. al (2005) Oncogene 24:5333-5343Salomon D. et. al (1992) J. Cell Sci. 102:7-17The MGC Project Team (2004) Genome Res. 14:2121-2127
Buffer:
Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Concentration:
1 mg/mL
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
N-Cadherin (CD325) antibody was raised against a peptide sequence around aa.800~804 (A-I-K-P-V) derived from Human N-Cadherin.
NCBI Gene ID #:
1000
NCBI Official Name:
cadherin 2, type 1, N-cadherin (neuronal)
NCBI Official Symbol:
CDH2
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
140 kDa
Protein Accession #:
NP_001783.2
Protein GI Number:
14589889
Purification:
Antibodies were purified by affinity-chromatography using epitope-specific peptide.
Research Area:
Stem Cell
SPECIFICITY:
This antibody detects endogenous level of total N-Cadherin protein.
Swissprot #:
P19022