Paxillin Antibody

ProSci
Product Code: PSI-79-693
Product Group: Primary Antibodies
Supplier: ProSci
CodeSizePrice
PSI-79-693-0.1mg0.1mg£481.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Rabbit
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Applications:
  • Immunofluorescence (IF)
  • Western Blot (WB)
Storage:
Store antibody at -20˚C for up to one year.

Images

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Western blot analysis of lysed extracts from HUVEC cells using Paxillin (Ab-88).
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Immunofluorescence staining of methanol-fixed HeLa cells using Paxillin (Ab-88).

Western blot analysis of lysed extracts from HUVEC cells using Paxillin (Ab-88).
Immunofluorescence staining of methanol-fixed HeLa cells using Paxillin (Ab-88).

Further Information

Additional Names:
CMKBR5, PAXI, PXN
Application Note:
Western Blot: 1:500~1:1000, Immunofluorescence: 1:50~1:100
Background:
Cytoskeletal protein involved in actin-membrane attachment at sites of cell adhesion to the extracellular matrix (focal adhesion).
Background References:
  • Burridge, K. et al. (1992) J. Cell Biol. 119, 893-903. Bellis, S. L. et al. (1995) J. Biol. Chem. 270, 17437-17441Schaller, M. D. and Parsons, J. T. (1995) Mol. Cell. Biol. 15, 2635-2645. Turner, C. E. (2000) J. Cell Sci. 113, 4139-4140.
Buffer:
Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Concentration:
1 mg/mL
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
Paxillin (Ab-88) antibody was raised against a peptide sequence around aa.86~90 (P-V-Y-G-S) derived from Human Paxillin.
NCBI Gene ID #:
5829
NCBI Official Name:
paxillin
NCBI Official Symbol:
PXN
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
68 kDa
Protein Accession #:
NP_001074324.1
Protein GI Number:
170932514
Purification:
Antibodies were purified by affinity-chromatography using epitope-specific peptide.
Research Area:
Other
SPECIFICITY:
This antibody detects endogenous level of total Paxillin protein.
Swissprot #:
P49023