PKCzeta Antibody

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ProSci
Product Code: PSI-79-411
Product Group: Primary Antibodies
Supplier: ProSci
CodeSizePrice
PSI-79-411-0.1mg0.1mg£481.00
Quantity:
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Overview

Host Type: Rabbit
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
  • Human
  • Mouse
  • Rat
Applications:
  • Immunohistochemistry (IHC)
  • Western Blot (WB)
Storage:
Store antibody at -20˚C for up to one year.

Images

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Western blot analysis of extract from 293 cells and HeLa using PKCzeta (Ab-410).
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Immunohistochemical analysis of paraffin-embedded human lung carcinoma tissue using PKCzeta (Ab-410).
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Western blot analysis of extract from 293 cells and HeLa using PKCzeta (Ab-410).
Immunohistochemical analysis of paraffin-embedded human lung carcinoma tissue using PKCzeta (Ab-410).

Documents

Further Information

Additional Names:
PKC2, PKC-ZETA, GAD65, PKC2, PRKCZ
Application Note:
Western Blot: 1:500~1:1000, Immunohistochemistry: 1:50~1:100
Background:
This is a calcium-independent, phospholipid-dependent, serine- and threonine-specific enzyme. PKC is activated by diacylglycerol which in turn phosphorylates a range of cellular proteins. PKC also serves as the receptor for phorbol esters, a class of tumor promoters. Subunit of a quaternary complex that plays a central role in epithelial cell polarization.
Background References:
  • Parmentier JH, et al. (2004) BMC Cell Biol; 5: 4. Castrillo A, et al. (2003) Mol Cell Biol; 23 (4): 1196-1208. Paramio JM, et al. ( 2001) Mol Cell Biol; 21 (21): 7449-7459. Braiman L, et al. (2001) Mol Cell Biol; 21 (22): 7852-7861.
Buffer:
Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Concentration:
1 mg/mL
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
PKCzeta (Ab-410) antibody was raised against a peptide sequence around aa. 408~412 ( T-S-T-F-C) derived from PKCzeta .
NCBI Gene ID #:
5590
NCBI Official Name:
protein kinase C, zeta
NCBI Official Symbol:
PRKCZ
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
78 kDa
Protein Accession #:
NP_002735.3
Protein GI Number:
52486327
Purification:
Antibodies were purified by affinity-chromatography using epitope-specific peptide.
Research Area:
Neuroscience
SPECIFICITY:
This antibody detects endogenous levels of total PKCzeta protein.
Swissprot #:
Q05513