PLC-gamma2 Antibody

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ProSci
Product Code: PSI-79-427
Product Group: Primary Antibodies
Supplier: ProSci
CodeSizePrice
PSI-79-427-0.1mg0.1mg£481.00
Quantity:
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Overview

Host Type: Rabbit
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
  • Human
  • Mouse
  • Rat
Applications:
  • Immunofluorescence (IF)
  • Immunohistochemistry (IHC)
Storage:
Store antibody at -20˚C for up to one year.

Images

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Immunohistochemical analysis of paraffin-embedded human lung carcinoma tissue using PLC-γ2 (Ab-1217).
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Immunofluorescence staining of methanol-fixed HeLa cells using PLC-γ2 (Ab-1217).
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Immunohistochemical analysis of paraffin-embedded human lung carcinoma tissue using PLC-γ2 (Ab-1217).
Immunofluorescence staining of methanol-fixed HeLa cells using PLC-γ2 (Ab-1217).

Documents

Further Information

Additional Names:
FCAS3, APLAID, PLC-IV, PLC-gamma-2, Afh, Fbl3a, Fbxl3a, Ovtm, PLC-gamma2, Phospholipase C-gamma-2
Application Note:
Immunohistochemistry: 1:50~1:100, Immunofluorescence: 1:100~1:200
Background:
The production of the second messenger molecules diacylglycerol. (DAG) and inositol 1, 4, 5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. It is a crucial enzyme in transmembrane signaling.
Background References:
  • Singer, W. D. et al. (1997) Annu. Rev. Biochem. 66, 475-509. Smrcka, A. V. et al. (1991) Science 251, 804-807. Yue, C. et al. (2000) J. Biol. Chem. 275, 30220-30225. Watanabe, D. et al. (2001) J. Biol. Chem. 276, 38595-38601.
Buffer:
Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Concentration:
1 mg/mL
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
PLC-gamma2 (Ab-1217) antibody was raised against a peptide sequence around aa.1215~1219 (F-L-Y-D-T) derived from Human PLCγ2.
NCBI Gene ID #:
5336
NCBI Official Name:
phospholipase C, gamma 2 (phosphatidylinositol-specific)
NCBI Official Symbol:
PLCG2
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
150 kDa
Protein Accession #:
NP_002652.2
Protein GI Number:
117320537
Purification:
Antibodies were purified by affinity-chromatography using epitope-specific peptide.
Research Area:
Neuroscience
SPECIFICITY:
This antibody detects endogenous level of total PLC-γ2 protein.
Swissprot #:
P16885