PPARgamma Antibody
| Code | Size | Price |
|---|
| PSI-79-749-0.1mg | 0.1mg | £481.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
- Human
- Mouse
Application: Western Blot (WB)
Storage:
Store antibody at -20˚C for up to one year.
Documents
Further Information
Additional Names:
GLM1, CIMT1, NR1C3, PPARG1, PPARG2, PPARgamma, MAPTL, MTBT1, TAU, GLM1, PPARG
Application Note:
Western Blot: 1:500~1:1000
Background:
Receptor that binds peroxisome proliferators such as hypolipidemic drugs and fatty acids. Once activated by a ligand, the receptor binds to a promoter element in the gene for acyl-CoA oxidase and activates its transcription. It therefore controls the peroxisomal beta-oxidation pathway of fatty acids. Key regulator of adipocyte differentiation and glucose homeostasis.
Background References:
- "Identification, characterization, and tissue distribution of human peroxisome proliferator-activated receptor (PPAR) isoforms PPARgamma2 versus PPARgamma1 and activation with retinoid X receptor agonists and antagonists. "Mukherjee R., Jow L., Croston G. E., et al. J. Biol. Chem. 272:8071-8076 (1997) "Cloning and characterization of RAP250, a nuclear receptor coactivator. "Caira F., Antonson P., Pelto-Huikko M., et al. J. Biol. Chem. 275:5308-5317 (2000) "Identification of protein arginine methyltransferase 2 as a coactivator for estrogen receptor alpha. "Qi C., Chang J., Zhu Y., et al. J. Biol. Chem. 277:28624-28630 (2002)
Buffer:
Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Concentration:
1 mg/mL
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
PPARgamma antibody was raised against a peptide sequence around aa.50~54 (L-S-V-M-E) derived from Human PPARγ.
NCBI Gene ID #:
5468
NCBI Official Name:
peroxisome proliferator-activated receptor gamma
NCBI Official Symbol:
PPARG
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
53 57 kDa
Protein Accession #:
NP_005028.4
Protein GI Number:
116284368
Purification:
Antibodies were purified by affinity-chromatography using epitope-specific peptide.
Research Area:
Stem Cell
SPECIFICITY:
This antibody detects endogenous levels of total PPARγ protein.
Swissprot #:
P37231