PRL-3 Antibody

ProSci
Product Code: PSI-79-623
Product Group: Primary Antibodies
Supplier: ProSci
CodeSizePrice
PSI-79-623-0.1mg0.1mg£481.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Rabbit
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
  • Human
  • Mouse
Application: Western Blot (WB)
Storage:
Store antibody at -20˚C for up to one year.

Images

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Western blot analysis of extract from LX-2 cells transfected with PRL-3 using PRL-3 Antibody.

Western blot analysis of extract from LX-2 cells transfected with PRL-3 using PRL-3 Antibody.

Further Information

Additional Names:
PRL3, PRL-3, PRL-R, HDACL1, CDA07, protein tyrosine phosphatase type IVA, PRL3, PTP4A3
Application Note:
Western Blot: 1:500~1:1000
Background:
Protein tyrosine phosphatase which stimulates progression from G1 into S phase during mitosis. Enhances cell proliferation, cell motility and invasive activity, and promotes cancer metastasis. May be involved in the progression of cardiac hypertrophy by inhibiting intracellular calcium mobilization in response to angiotensin II.
Background References:
  • Matter W. F. et. al. Biochem. Biophys. Res. Commun. 283:1061-1068 (2001) Wang J. et. al. J. Biol. Chem. 277:46659-46668 (2002)
Buffer:
Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Concentration:
1 mg/mL
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
PRL-3 antibody was raised against a peptide sequence around aa. 161-166 (K-D-P-H-T) derived from Human PTP4A3.
NCBI Gene ID #:
11156
NCBI Official Name:
protein tyrosine phosphatase type IVA, member 3
NCBI Official Symbol:
PTP4A3
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
22 kDa
Protein Accession #:
NP_116000
Protein GI Number:
14589856
Purification:
Antibodies were purified by affinity-chromatography using epitope-specific peptide.
Research Area:
Apoptosis,Cancer
SPECIFICITY:
This antibody detects transfected PRL-3 protein.
Swissprot #:
O75365